(Q33525124)

English

HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

1 reference

1 reference

7-(1,3-Benzodioxol-5-yl)-1-piperidin-1-ylhepta-2,4,6-trien-1-one

1 reference

1 reference

5-(2H-1,3-Benzodioxol-5-YL)-1-(piperidin-1-YL)pent-2-EN-1-one

1 reference

Piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-

1 reference

5-(1,3-Benzodioxol-5-yl)-1-pyrrolidin-1-ylpenta-2,4-dien-1-one

1 reference

piperlonguminine

1 reference

Matthias Hamburger

6

object named as

Matthias Hamburger

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

author name string

Janine Zaugg

1

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Igor Baburin

2

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Barbara Strommer

3

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Hyun-Jung Kim

4

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Steffen Hering

5

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

publication date

19 January 2010

1 reference

16 September 2022

full work available at URL

https://europepmc.org/articles/pmc3196983?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/np900656g?email=unpaywall_01@example.com

Journal of Natural Products

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

73

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

185-191

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/np900656g?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

The subunit arrangement and assembly of ionotropic receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Benzodiazepines in epilepsy: pharmacology and pharmacokinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Bioavailability of curcumin: problems and promises

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

GABAA receptors as targets for novel anxiolytic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Automated fast perfusion of Xenopus oocytes for drug screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

GABA-A receptors: a viable target for novel anxiolytics?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Pharmacological properties of GABAA receptors containing gamma1 subunits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Benzodiazepines and anxiety disorders: a review for the practicing physician

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Piperlonguminine from Piper longum with inhibitory effects on alpha-melanocyte-stimulating hormone-induced melanogenesis in melanoma B16 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Preparative isolation and purification of amides from the fruits of Piper longum L. by upright counter-current chromatography and reversed-phase liquid chromatography.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Development of effective therapeutics targeting the GABAA receptor: naturally occurring alternatives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Immunomodulatory and antitumor activity of Piper longum Linn. and piperine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Subunit composition, distribution and function of GABA(A) receptor subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

A review of pharmacology and clinical use of piperine and its derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

21 June 2018

Amides from Piper capense with CNS activity - a preliminary SAR analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Ethnopharmacology of Q'eqchi' Maya antiepileptic and anxiolytic plants: effects on the GABAergic system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Piperine, the potential functional food for mood and cognitive disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Analysis by HPLC and LC/MS of pungent piperamides in commercial black, white, green, and red whole and ground peppercorns.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Piperine: researchers discover new flavor in an ancient spice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

HPLC-based activity profiling of Salvia miltiorrhiza for MAO A and iNOS inhibitory activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Analysis of the set of GABA(A) receptor genes in the human genome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

New amide alkaloids from the roots of Piper nigrum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Cytotoxic amides from Piper sintenense.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Larvicidal activity of isobutylamides identified in Piper nigrum fruits against three mosquito species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Identification and isolation of the cyclooxygenase-2 inhibitory principle in Isatis tinctoria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196983

31 October 2018

Piperine inhibits gastric emptying and gastrointestinal transit in rats and mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20085307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BI-32169, a Bicyclic 19-Peptide with Strong Glucagon Receptor Antagonist Activity fromStreptomycessp.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20085307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticonvulsant activity of piperine on seizures induced by excitatory amino acid receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/20085307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant-like effects of piperine and its derivative, antiepilepsirine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20085307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/NP900656G

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33525124&oldid=2106453399"