(Q33525709)

English

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS).

scientific article

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS)

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS). (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS) (English)

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polycystic ovary syndrome

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based on heuristic

inferred from title

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based on heuristic

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insulin resistance

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based on heuristic

inferred from title

polycystic ovary

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based on heuristic

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11

object named as

Thomas Illig

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14

object named as

Anke Hinney

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Johannes Hebebrand

13

object named as

Johannes Hebebrand

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Harald Grallert

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object named as

Harald Grallert

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Europe PubMed Central

PubMed publication ID

27 July 2017

object named as

André Scherag

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object named as

Susann Scherag

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Europe PubMed Central

PubMed publication ID

27 July 2017

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object named as

Susanne Hahn

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Europe PubMed Central

PubMed publication ID

27 July 2017

12

object named as

Klaus Mann

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Europe PubMed Central

PubMed publication ID

27 July 2017

author name string

Susanne Tan

1

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Europe PubMed Central

PubMed publication ID

27 July 2017

Onno Eilard Janssen

3

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Europe PubMed Central

PubMed publication ID

27 July 2017

Harald Lahner

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Europe PubMed Central

PubMed publication ID

27 July 2017

Tiina Dietz

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1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Carla Ivane Ganz Vogel

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1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Rainer Kimmig

10

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Europe PubMed Central

PubMed publication ID

27 July 2017

Anke Hinney

14

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language of work or name

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publication date

21 January 2010

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

BMC Medical Genetics

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Europe PubMed Central

PubMed publication ID

27 July 2017

11

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Europe PubMed Central

PubMed publication ID

27 July 2017

1

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12

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Europe PubMed Central

PubMed publication ID

27 July 2017

https://scigraph.springernature.com/pub.10.1186/1471-2350-11-12

0 references

Milder forms of atherogenic dyslipidemia in ovulatory versus anovulatory polycystic ovary syndrome phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Common variants near MC4R are associated with fat mass, weight and risk of obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Metformin improves polycystic ovary syndrome symptoms irrespective of pre-treatment insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Genome-wide association with diabetes-related traits in the Framingham Heart Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

The common genetic variant upstream of INSIG2 gene is not associated with obesity in Indian population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Variants of the transcription factor 7-like 2 gene (TCF7L2) are strongly associated with type 2 diabetes but not with the metabolic syndrome in the MONICA/KORA surveys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Comment on "A common genetic variant is associated with adult and childhood obesity"

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Effects of the diabetes linked TCF7L2 polymorphism in a representative older population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

KORA--a research platform for population based health research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Therapeutic strategies based on glucagon-like peptide 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

The prevalence and features of the polycystic ovary syndrome in an unselected population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Molecular progress in infertility: polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Comparison of tests of beta-cell function across a range of glucose tolerance from normal to diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

21 June 2018

Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

FTO gene associates to metabolic syndrome in women with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

A common genetic variant is associated with adult and childhood obesity

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Comment on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity"

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Evidence of an influence of a polymorphism near the INSIG2 on weight loss during a lifestyle intervention in obese children and adolescents

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human -Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population based surveys

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Significant association of a M129V independent polymorphism in the 5' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Endocrine and metabolic differences among phenotypic expressions of polycystic ovary syndrome according to the 2003 Rotterdam consensus criteria

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

The FTO gene modifies weight, fat mass and insulin sensitivity in women with polycystic ovary syndrome, where its role may be larger than in other phenotypes.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Beta cell glucose sensitivity is decreased by 39% in non-diabetic individuals carrying multiple diabetes-risk alleles compared with those with no risk alleles.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-12

21 January 2018

Metabolic characteristics of women with polycystic ovaries and oligo-amenorrhoea but normal androgen levels: implications for the management of polycystic ovary syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

31 October 2018

Defects in insulin receptor signaling in vivo in the polycystic ovary syndrome (PCOS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

31 October 2018

A critical evaluation of simple methods for the estimation of free testosterone in serum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

31 October 2018

Molecular scanning of the insulin receptor gene in women with polycystic ovarian syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824654

31 October 2018

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20092643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligoanovulation with polycystic ovaries but not overt hyperandrogenism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20092643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine mapping of genetic susceptibility to polycystic ovary syndrome on chromosome 19p13.2 and tests for regulatory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20092643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comment on "A common genetic variant is associated with adult and childhood obesity"

1 reference

https://pubmed.ncbi.nlm.nih.gov/20092643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2350-11-12

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Dimensions Publication ID

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2350-11-12

9 September 2019

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

ResearchGate publication ID

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