(Q33534117)

27 July 2017

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title

Downstream factors in transforming growth factor-beta family signaling (English)

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27 July 2017

Visser JA

1

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27 July 2017

Themmen AP

series ordinal

2

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27 July 2017

publication date

1 November 1998

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Molecular and Cellular Endocrinology

27 July 2017

published in

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27 July 2017

volume

146

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27 July 2017

issue

1-2

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27 July 2017

page(s)

7-17

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TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

27 July 2017

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7 January 2021

The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family

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7 January 2021

Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-beta through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) signaling pathway

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7 January 2021

Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor beta-mediated signaling

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7 January 2021

Raf meets Ras: completing the framework of a signal transduction pathway

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7 January 2021

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

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7 January 2021

The GTPase superfamily: a conserved switch for diverse cell functions

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7 January 2021

Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex.

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7 January 2021

A transcriptional partner for MAD proteins in TGF-beta signalling

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7 January 2021

Smad4 and FAST-1 in the assembly of activin-responsive factor

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7 January 2021

Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins

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7 January 2021

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

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7 January 2021

Identification of a Drosophila activin receptor

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7 January 2021

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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7 January 2021

Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

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7 January 2021

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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7 January 2021

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

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7 January 2021

Determination of type I receptor specificity by the type II receptors for TGF-beta or activin

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7 January 2021

The pathway to signal achievement

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7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

The GS domain of the transforming growth factor-beta type I receptor is important in signal transduction

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

TGFbeta regulation of mitogen-activated protein kinases in human breast cancer cells

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

G proteins: transducers of receptor-generated signals

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Transcriptional regulation by extracellular signals: mechanisms and specificity

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Transforming growth factor beta 1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s).

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Smad6 inhibits signalling by the TGF-beta superfamily

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity

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7 January 2021

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

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7 January 2021

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Sounding the alarm: protein kinase cascades activated by stress and inflammation

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7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

1 reference

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7 January 2021

Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1

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7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

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7 January 2021

Combined BMP-2 and FGF-4, but neither factor alone, induces cardiogenesis in non-precardiac embryonic mesoderm.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Signaling by chimeric erythropoietin-TGF-beta receptors: homodimerization of the cytoplasmic domain of the type I TGF-beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Reduction of epidermal growth factor receptor phosphorylation by activated Mullerian inhibiting substance is vanadate-sensitive

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

The transforming growth factor-beta family

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

TGF-beta signalling through the Smad pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Signal transduction. How receptors turn Ras on.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Trying on a new pair of SH2s

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Extracellular signal-regulated kinase and the small GTP-binding protein, Rac, contribute to the effects of transforming growth factor-beta1 on gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Role of receptor complexes in resistance or sensitivity to growth inhibition by TGF beta in intestinal epithelial cell clones.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation

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https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

FGF-4 and BMP-2 have opposite effects on limb growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Mad-related genes in the human

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Serine/threonine kinase receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Characterization of type I receptors for transforming growth factor-beta and activin

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Daughters against dpp modulates dpp organizing activity in Drosophila wing development

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Signaling activity of homologous and heterologous transforming growth factor-beta receptor kinase complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Cloning and characterization of a novel member of the human Mad gene family (MADH6)

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Involvement of p21ras in Xenopus mesoderm induction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Mechanism of activation of the TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Involvement of Ras/Raf/AP-1 in BMP-4 signaling during Xenopus embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2898%2900198-1

7 January 2021

10.1016/S0303-7207(98)00198-1

Identifiers

DOI

1 reference

27 July 2017

1 reference