(Q33537594)

27 July 2017

title

Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9). (English)

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27 July 2017

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10

Benjamin F Cravatt

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27 July 2017

Daniel A Bachovchin

1

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27 July 2017

Monique R Wolfe

2

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27 July 2017

Kim Masuda

3

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27 July 2017

Steven J Brown

4

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27 July 2017

Timothy P Spicer

5

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27 July 2017

Virneliz Fernandez-Vega

6

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27 July 2017

Peter Chase

7

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27 July 2017

Peter S Hodder

8

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27 July 2017

Hugh Rosen

9

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27 July 2017

language of work or name

English

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publication date

6 February 2010

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Bioorganic & Medicinal Chemistry Letters

27 July 2017

published in

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27 July 2017

volume

20

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27 July 2017

issue

7

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27 July 2017

page(s)

2254-2258

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RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia

27 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Activity-based protein profiling: from enzyme chemistry to proteomic chemistry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

High-throughput screening assays for the identification of chemical probes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Scaffold composition and biological relevance of screening libraries.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Relating protein pharmacology by ligand chemistry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Mechanism-based profiling of enzyme families

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Structural basis for inhibition of protein synthesis by emetine and cycloheximide based on an analogy between ipecac alkaloids and glutarimide antibiotics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Substrate activity screening: a fragment-based method for the rapid identification of nonpeptidic protease inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Chemical approaches for functionally probing the proteome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Activity-based protein profiling: the serine hydrolases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Potent inhibitors of lipoprotein-associated phospholipase A(2): benzaldehyde O-heterocycle-4-carbonyloxime.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Mapping enzyme active sites in complex proteomes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843764

The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20207142

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2010.02.011

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27 July 2017

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27 July 2017

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