(Q33538230)

27 July 2017

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title

Kinetics of hydrolysis and reaction of aflatoxin B1 exo-8,9-epoxide and relevance to toxicity and detoxication (English)

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27 July 2017

Guengerich FP

1

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27 July 2017

Johnson WW

series ordinal

2

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27 July 2017

language of work or name

English

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publication date

1 February 1999

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27 July 2017

published in

Drug Metabolism Reviews

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27 July 2017

volume

31

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27 July 2017

issue

1

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27 July 2017

page(s)

141-158

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

27 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Activation and detoxication of aflatoxin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Aflatoxin B1 8,9-epoxide hydrolysis in the presence of rat and human epoxide hydrolase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Reaction of aflatoxin B1 exo-8,9-epoxide with DNA: kinetic analysis of covalent binding and DNA-induced hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Genotoxic and mutagenic activation of aflatoxin B1 by constitutive forms of cytochrome P-450 in rat liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Prostaglandin H synthase-dependent epoxidation of aflatoxin B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Oxidation of aflatoxins and sterigmatocystin by human liver microsomes: significance of aflatoxin Q1 as a detoxication product of aflatoxin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

The endo-8,9-epoxide of aflatoxin B1: a new metabolite

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Some mass-spectral and n.m.r. analytical studies of a glutathione conjugate of aflatoxin B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Contribution of the glutathione S-transferases to the mechanisms of resistance to aflatoxin B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Comparison of the aflatoxin B1-8,9-epoxide conjugating activities of two bacterially expressed alpha class glutathione S-transferase isozymes from mouse and rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Alteration of the aflatoxin cyclopentenone ring to a delta-lactone reduces intercalation with DNA and decreases formation of guanine N7 adducts by aflatoxin epoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Acidic domains around nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Conjugation of Highly Reactive Aflatoxin B1exo-8,9-Epoxide Catalyzed by Rat and Human Glutathione Transferases: Estimation of Kinetic Parameters†

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Aflatoxin B1 epoxidation catalysed by partially purified human liver lipoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: correlation with metabolic activation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Isolation and characterization of the major serum albumin adduct formed by aflatoxin B1 in vivo in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

The major metabolite of aflatoxin B1 in the rat is a glutathione conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Glutathione conjugation of aflatoxin B1 exo- and endo-epoxides by rat and human glutathione S-transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Activation and deactivation of aflatoxin B1 in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

Application of the Theory of Diffusion-controlled Reactions to Enzyme Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101911

21 January 2018

Identifiers

DOI

10.1081/DMR-100101911

1 reference

27 July 2017

1 reference