(Q24299140)

English

Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver

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scholarly article

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Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver (English)

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cytochrome P450 family 3 subfamily A member 4

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GOA release 2020-03-11

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GOA release 2020-03-11

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based on heuristic

inferred from title

F. Peter Guengerich

2

object named as

F P Guengerich

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author name string

T Shimada

1

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language of work or name

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publication date

January 1989

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Proceedings of the National Academy of Sciences of the United States of America

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86

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462-5

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2

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Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

19 March 2017

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

19 March 2017

Aflatoxin metabolism in humans: detection of metabolites and nucleic acid adducts in urine by affinity chromatography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

19 March 2017

Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

27 September 2017

Identification of an inducible form of cytochrome P-450 in human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

27 September 2017

Isolation and sequence determination of a cDNA clone related to human cytochrome P-450 nifedipine oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

27 September 2017

Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

27 September 2017

Sterigmatocystin-DNA interactions: identification of a major adduct formed after metabolic activation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

27 September 2017

Aflatoxin B1-2,3-oxide as a probable intermediate in the covalent binding of aflatoxins B1 and B2 to rat liver DNA and ribosomal RNA in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

27 September 2017

Measurement of urinary 6-?-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

27 September 2017

Genetic predisposition to bladder cancer: ability to hydroxylate debrisoquine and mephenytoin as risk factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

27 September 2017

Some observations on the oxidation phenotype status of Nigerian patients presenting with cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Microsome-dependent binding of aflatoxin B1 to DNA, RNA, polyribonucleotides and protein in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Carcinogenicity of sterigmatocystin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

The P450 gene superfamily: recommended nomenclature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Modulation of rabbit and human hepatic cytochrome P-450-catalyzed steroid hydroxylations by alpha-naphthoflavone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

SOS-inducing activity of chemical carcinogens and mutagens in Salmonella typhimurium TA1535/pSK1002: examination with 151 chemicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Purification and characterization of ethanol-inducible human hepatic cytochrome P-450HLj

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Cytochrome P-450-mediated activation of procarcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/pSK1002.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Genotoxic and mutagenic activation of aflatoxin B1 by constitutive forms of cytochrome P-450 in rat liver microsomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Genotoxic effects of a variety of sterigmatocystin-related compounds in the hepatocyte/DNA-repair test and the Salmonella microsome assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

30 May 2018

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286490

29 November 2018

P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16 alpha-hydroxylase of dehydroepiandrosterone 3-sulfate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of 17 alpha-ethynylestradiol by human liver cytochrome P-450

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aflatoxin B1-2,3-oxide: evidence for its formation in rat liver in vivo and by human liver microsomes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction III binding of [14C] aflatoxin B1 to rat liver macromolecules by phenobarbitone pretreatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and inhibition of benzo(a)pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-induction by triacetyloleandomycin of its own transformation into a metabolite forming a stable 456 nm-absorbing complex with cytochrome P-450

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity in the activation and inhibition by flavonoids of benzo[a]pyrene hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificity of human liver cytochrome P-450 debrisoquine 4-hydroxylase probed using immunochemical inhibition and chemical modeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of quinidine by human liver cytochrome P-450

1 reference

https://pubmed.ncbi.nlm.nih.gov/2492107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.86.2.462

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1989PNAS...86..462S

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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