(Q39111)

nifedipine (English)

3 October 2016

C₁₇H₁₈N₂O₆

1 reference

nifedipine (English)

19 November 2016

CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC

1 reference

nifedipine (English)

19 November 2016

30 milligram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=C08CA05

30 milligram

route of administration

parenteral route of administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=C08CA05

1 reference

14 February 2018

1 reference

14 February 2018

1 reference

14 February 2018

1 reference

14 February 2018

1 reference

14 February 2018

World Health Organisation international non-proprietary name

nifedipine (English)

1 reference

A community-driven global reconstruction of human metabolism.

nifedipine (English)

3 October 2016

1 reference

medical condition treated

arterial hypertension

2 references

13 December 2016

Drug Indications Extracted from FAERS

2 October 2018

1 reference

significant drug interaction

13 December 2016

doxazosin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

itraconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

itraconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

itraconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

posaconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

posaconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

posaconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

voriconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

voriconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

voriconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ritonavir

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ritonavir

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ritonavir

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cobicistat

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cobicistat

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cobicistat

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Ketoconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Ketoconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Ketoconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

headache disorder

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tachycardia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

peripheral edema

1 reference

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

Calcium voltage-gated channel subunit alpha1 S

1 reference

Calcium voltage-gated channel subunit alpha1 C

17 August 2016

1 reference

Calcium voltage-gated channel subunit alpha1 D

17 August 2016

1 reference

Calcium voltage-gated channel subunit alpha1 F

17 August 2016

1 reference

17 August 2016

Glycine receptor alpha 1

1 reference

17 August 2016

Glycine receptor alpha 3

1 reference

17 August 2016

Glycine receptor beta

1 reference

Potassium voltage-gated channel, shaker-related subfamily, member 1

17 August 2016

1 reference

Potassium voltage-gated channel subfamily A member 5

17 August 2016

1 reference

Potassium voltage-gated channel, shaker-related subfamily, member 7

17 August 2016

1 reference

Potassium voltage gated channel, Shaw-related subfamily, member 1

17 August 2016

1 reference

nuclear receptor subfamily 1 group I member 2

17 August 2016

1 reference

Transient receptor potential cation channel subfamily M member 3

17 August 2016

1 reference

17 August 2016

legal status (medicine)

boxed warning

1 reference

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

LiverTox likelihood score

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

LiverTox toxicity likelihood category B

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Nifedipine

last update

11 January 2017

subject has role

calcium channel blocker

2 references

5 March 2018

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D009543

tocolytic uterine relaxants

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D009543

15 March 2018

developmental toxicant

start time

29 January 1999

1 reference

18 March 2020

male reproductive toxicant

start time

29 January 1999

1 reference

18 March 2020

female reproductive toxicant

start time

29 January 1999

1 reference

18 March 2020

Food and Drug Administration

0 references

NIFEdipine

subject named as

Nifedipine

1 reference

https://www.fda.gov/drugs/medication-errors-related-cder-regulated-drug-products/fda-name-differentiation-project

InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3

2 September 2022

MCN code

2933.39.43

0 references

0 references

0 references

0 references

Nifedipine

0 references

Identifiers

InChI

1 reference

nifedipine (English)

19 November 2016

2 references

nifedipine (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

21829-25-4

1 reference

nifedipine (English)

19 November 2016

1 reference

Nifedipine (English)

19 November 2016

2 references

nifedipine (English)

19 November 2016

Reaxys registry number

497773

1 reference

nifedipine (English)

3 October 2016

mapping relation type

2 references

NIFEDIPINE (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3

1 reference

NIFEDIPINE (English)

19 November 2016

2 references

inferred from InChIKey

splash10-0v4i-1691000000-c4842fe2c3070d6e90dd

1 reference

0 references

0 references

1 reference

Hazardous Substances Data Bank

28 October 2019

Nifedipine (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

1 reference

nifedipine (English)

ECHA Substance Infocard ID

19 November 2016

100.040.529

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Nifedipine (English)

CAS no.: 21829-25-4 (English)

1 reference

Nifedipine (English)

publication date

17 November 2015

1 reference

nifedipine (English)

19 November 2016

Nifedipine

0 references

0 references

0 references

1 reference

nifedipine (English)

19 November 2016

1 reference

Human Metabolome Database ID

HMDB0015247

2 references

based on heuristic

inferred from InChIKey

2 references

nifedipine (English)

19 November 2016

MedlinePlus drug identifier

0 references

1 reference

nifedipine (English)

19 November 2016

0 references

1 reference

1 reference

nifedipine (English)

3 October 2016

1 reference

nifedipine (English)

3 October 2016

0 references

1 reference

6 January 2020

electronic Essential Medicines List medicine ID

0 references

1 reference

28 October 2013

1 reference

9 July 2020

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

UMLS CUI

C0028066

1 reference

nifedipine (English)

19 November 2016

0 references

WordNet 3.1 Synset ID

03829554-n

1 reference

nifedipiini

nifedipin

nifedipine

1 reference

YSO-Wikidata mapping project