(Q33540084)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

review article

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title

Telomere maintenance mechanisms and cellular immortalization (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

L M Colgin

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

publication date

1 February 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

Current Opinion in Genetics & Development

11 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

97-103

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena

11 November 2019

cites work

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7 January 2021

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

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7 January 2021

Normal human chromosomes have long G-rich telomeric overhangs at one end

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7 January 2021

Origin of Concatemeric T7DNA

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7 January 2021

Evidence for a new step in telomere maintenance

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7 January 2021

Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae

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7 January 2021

Coordinate regulation of G- and C strand length during new telomere synthesis

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7 January 2021

Addition of telomere-associated HeT DNA sequences "heals" broken chromosome ends in Drosophila

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7 January 2021

Chromosome end elongation by recombination in the mosquito Anopheles gambiae

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7 January 2021

An alternative pathway for yeast telomere maintenance rescues est1- senescence

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7 January 2021

Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase

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7 January 2021

Telomere loss: mitotic clock or genetic time bomb?

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

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7 January 2021

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Human telomerase contains evolutionarily conserved catalytic and structural subunits

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7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

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7 January 2021

The catalytic subunit of yeast telomerase

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7 January 2021

The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex

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7 January 2021

Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

The telomerase reverse transcriptase: components and regulation

1 reference

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7 January 2021

The RNA component of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

A mammalian telomerase-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Developmentally programmed assembly of higher order telomerase complexes with distinct biochemical and structural properties

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Reconstitution of human telomerase activity in vitro

1 reference

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7 January 2021

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

1 reference

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7 January 2021

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Inhibition of telomerase activity by PKC inhibitors in human nasopharyngeal cancer cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Mechanism of telomerase induction during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Telomerase is controlled by protein kinase Calpha in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Myc activates telomerase

1 reference

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7 January 2021

The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

1 reference

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7 January 2021

Telomere length dynamics in telomerase-positive immortal human cell populations.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Dissociation of telomere dynamics from telomerase activity in human thyroid cancer cells.

1 reference

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7 January 2021

A mammalian factor that binds telomeric TTAGGG repeats in vitro

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7 January 2021

TRF1, a mammalian telomeric protein

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7 January 2021

TRF1 promotes parallel pairing of telomeric tracts in vitro

1 reference

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7 January 2021

Control of telomere length by the human telomeric protein TRF1

1 reference

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7 January 2021

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

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7 January 2021

Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase

1 reference

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7 January 2021

Telomeres: moonlighting by DNA repair proteins

1 reference

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7 January 2021

Telomeres and double-strand breaks: trying to make ends meet.

1 reference

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7 January 2021

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

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7 January 2021

The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Telomere maintenance is dependent on activities required for end repair of double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance

1 reference

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7 January 2021

The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Telomerase activity in normal and malignant hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

SV40-INDUCED TRANSFORMATION OF HUMAN DIPLOID CELLS: CRISIS AND RECOVERY

1 reference

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7 January 2021

Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells

1 reference

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7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

1 reference

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7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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7 January 2021

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

1 reference

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7 January 2021

In situ analysis of changes in telomere size during replicative aging and cell transformation

1 reference

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7 January 2021

Extra-chromosomal telomere repeat DNA in telomerase-negative immortalized cell lines

1 reference

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7 January 2021

Release of telomeric DNA from chromosomes in immortal human cells lacking telomerase activity

1 reference

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7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

A reassessment of the telomere hypothesis of senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Cellular senescence in telomerase-expressing Syrian hamster embryo cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980014-8

7 January 2021

Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks

1 reference

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7 January 2021

10.1016/S0959-437X(99)80014-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10072358%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference