(Q33541021)

27 July 2017

Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock (English)

1 reference

27 July 2017

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1 reference

Jixin Zhong

1

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author name string

Ping Yang

2

1 reference

27 July 2017

Kenjiro Muta

3

1 reference

27 July 2017

Robert Dong

4

1 reference

27 July 2017

Mario Marrero

5

1 reference

27 July 2017

Feili Gong

6

1 reference

27 July 2017

Cong-Yi Wang

7

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27 July 2017

language of work or name

English

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publication date

9 March 2010

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27 July 2017

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27 July 2017

5

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27 July 2017

3

1 reference

27 July 2017

e9593

1 reference

Creative Commons Attribution 4.0 International

27 July 2017

start time

9 March 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Jak2 inhibitors: rationale and role as therapeutic agents in hematologic malignancies

21 June 2018

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Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice

21 June 2018

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Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases

21 June 2018

1 reference

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Using innate immunity to characterize the host response to microbial invasion in severe sepsis

21 June 2018

1 reference

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The immunology of sepsis.

21 June 2018

1 reference

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Dendritic cells at the interface of innate and acquired immunity: the role for epigenetic changes

21 June 2018

1 reference

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Extracellular hmgb1 functions as an innate immune-mediator implicated in murine cardiac allograft acute rejection

21 June 2018

1 reference

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Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.

21 June 2018

1 reference

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Jak2: normal function and role in hematopoietic disorders

21 June 2018

1 reference

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Dendritic cells: translating innate to adaptive immunity.

21 June 2018

1 reference

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Mechanisms of mortality in early and late sepsis.

21 June 2018

1 reference

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Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Activation of dendritic cells via inhibition of Jak2/STAT3 signaling

21 June 2018

1 reference

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Cytokine inhibition of JAK-STAT signaling: a new mechanism of growth hormone resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Jak2 tyrosine kinase: a true jak of all trades?

21 June 2018

1 reference

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The interface between innate and adaptive immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Regulation of JAK-STAT signalling in the immune system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Sepsis and the dendritic cell

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

The chronic consequences of severe sepsis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Early IL-2 Production by Mouse Dendritic Cells Is the Result of Microbial-Induced Priming

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

The immunopathogenesis of sepsis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Inducible IL-2 production by dendritic cells revealed by global gene expression analysis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Critical advances in septicemia and septic shock

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Control of myeloid differentiation and survival by Stats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

The role of STATs in myeloid differentiation and leukemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Innate defenses in the liver during Listeria infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Jaks and STATs: biological implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Jak2 is essential for signaling through a variety of cytokine receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Roles of the JAK-STAT system in signal transduction via cytokine receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

JAK3: a novel JAK kinase associated with terminal differentiation of hematopoietic cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

CD8+ T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Gene delivery of indoleamine 2,3-dioxygenase prolongs cardiac allograft survival by shaping the types of T-cell responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Early- versus late-onset shock in European intensive care units.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Severe cutaneous papillomavirus disease after haemopoietic stem-cell transplantation in patients with severe combined immune deficiency caused by common gammac cytokine receptor subunit or JAK-3 deficiency

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Mechanistic insights into impaired dendritic cell function by rapamycin: inhibition of Jak2/Stat4 signaling pathway

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Sepsis and innate immunity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Innate immunity, Toll receptor and sepsis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

T helper cell subset ratios in patients with severe sepsis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

JAK/STAT signaling by cytokine receptors

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834745

The interplay of innate immunity, adaptive immunity, and autoimmunity

31 October 2018

1 reference

12 December 2020

Improving outcomes for severe sepsis and septic shock: tools for early identification of at-risk patients and treatment protocol implementation

1 reference

12 December 2020

Recognizing sepsis in the adult patient

1 reference

12 December 2020

The epidemiology of, and risk factors for, mortality from severe sepsis and septic shock in a tertiary-care university hospital setting

1 reference

12 December 2020

Selective defects of T lymphocyte function in patients with lethal intraabdominal infection

1 reference

12 December 2020

Expression of inflammatory cytokines by murine macrophages activated with a new synthetic lipopeptide JT3002

1 reference

12 December 2020

CD28 costimulation is required not only to induce IL-12 receptor but also to render janus kinases/STAT4 responsive to IL-12 stimulation in TCR-triggered T cells

1 reference

12 December 2020

IL-2 mediates adjuvant effect of dendritic cells

1 reference

12 December 2020

Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0009593

Identifiers

DOI

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27 July 2017

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27 July 2017

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