(Q33545484)

27 July 2017

title

Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells (English)

1 reference

27 July 2017

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1 reference

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Luigi Bubacco

6

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Mark R Cookson

series ordinal

5

object named as

Mark R Cookson

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27 July 2017

4

David W Miller

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27 July 2017

Marco Bisaglia

1

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27 July 2017

Elisa Greggio

series ordinal

2

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27 July 2017

Dragan Maric

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3

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27 July 2017

publication date

25 March 2010

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27 July 2017

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27 July 2017

volume

11

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27 July 2017

page(s)

41

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describes a project that uses

27 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2851596/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2202-11-41

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cites work

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons

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Structural insights on physiological functions and pathological effects of alpha-synuclein.

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Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

21 June 2018

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Dopamine differentially induces aggregation of A53T mutant and wild type alpha-synuclein: insights into the protein chemistry of Parkinson's disease

21 June 2018

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RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport.

21 June 2018

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Alpha-synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

21 June 2018

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alpha-Synuclein protects SH-SY5Y cells from dopamine toxicity

21 June 2018

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Development of an ischemic tolerance model in a PC12 cell line

21 June 2018

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Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 June 2018

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G209A mutant alpha synuclein expression specifically enhances dopamine induced oxidative damage

21 June 2018

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Differential cytotoxicity of human wild type and mutant alpha-synuclein in human neuroblastoma SH-SY5Y cells in the presence of dopamine

21 June 2018

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 June 2018

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alpha-Synuclein locus triplication causes Parkinson's disease

21 June 2018

1 reference

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Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress

21 June 2018

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Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

21 June 2018

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Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

21 June 2018

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Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

21 June 2018

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A role for alpha-synuclein in the regulation of dopamine biosynthesis

21 June 2018

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Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 June 2018

1 reference

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Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

21 June 2018

1 reference

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Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity

21 June 2018

1 reference

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Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

21 June 2018

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Extracellular toxicity of 6-hydroxydopamine on PC12 cells.

21 June 2018

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

21 June 2018

1 reference

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Dopamine quinone formation and protein modification associated with the striatal neurotoxicity of methamphetamine: evidence against a role for extracellular dopamine.

21 June 2018

1 reference

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Oxidative mechanisms in nigral cell death in Parkinson's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 June 2018

1 reference

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 June 2018

1 reference

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Alpha-synuclein in Lewy bodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Does oxidative stress participate in nerve cell death in Parkinson's disease?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with alpha-synuclein.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Role of alpha-synuclein in presynaptic dopamine recruitment.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851596

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity

31 October 2018

1 reference

12 December 2020

Covalent binding of catechols to proteins through the sulphydryl group

1 reference

12 December 2020

Localization of phosphoneuroprotein 14 (PNP 14) and its mRNA expression in rat brain determined by immunocytochemistry and in situ hybridization

1 reference

12 December 2020

Alpha-synuclein overexpression increases cytosolic catecholamine concentration

1 reference

12 December 2020

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2202-11-41

1 reference

Dimensions Publication ID

27 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2202-11-41

9 September 2019

1 reference

27 July 2017

1 reference