(Q33551720)

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Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile

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scholarly article

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Europe PubMed Central

28 July 2017

Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile (English)

1 reference

Europe PubMed Central

28 July 2017

1 reference

based on heuristic

inferred from title

David J. Waxman

4

1 reference

Europe PubMed Central

28 July 2017

author name string

M Chin

1

1 reference

Europe PubMed Central

28 July 2017

M Herscovitch

2

1 reference

Europe PubMed Central

28 July 2017

N Zhang

3

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Europe PubMed Central

28 July 2017

T D Gilmore

5

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Europe PubMed Central

28 July 2017

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20 April 2009

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Europe PubMed Central

28 July 2017

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Europe PubMed Central

28 July 2017

28

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Europe PubMed Central

28 July 2017

20

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Europe PubMed Central

28 July 2017

2100-2111

1 reference

Europe PubMed Central

28 July 2017

https://scigraph.springernature.com/pub.10.1038/onc.2009.74

0 references

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1 reference

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Deletion analysis and alternative splicing define a transactivation inhibitory domain in human oncoprotein REL

1 reference

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Repression of B-cell linker (BLNK) and B-cell adaptor for phosphoinositide 3-kinase (BCAP) is important for lymphocyte transformation by rel proteins

1 reference

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Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.

1 reference

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Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity

1 reference

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BCL2 expression is a prognostic marker for the activated B-cell-like type of diffuse large B-cell lymphoma

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MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells.

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Activation of NF-kappaB and inhibition of p53-mediated apoptosis by API2/mucosa-associated lymphoid tissue 1 fusions promote oncogenesis

1 reference

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Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways

1 reference

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The c-Rel transcription factor and B-cell proliferation: a deal with the devil

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Stable expression of the avian retroviral oncoprotein v-Rel in avian, mouse, and dog cell lines

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Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphoma

1 reference

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The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-kappaB signal transduction pathway

1 reference

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Immortalized embryonic mouse fibroblasts lacking the RelA subunit of transcription factor NF-kappaB have a malignantly transformed phenotype

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Genomic organization and expression of the rearranged REL proto-oncogene in the human B-cell lymphoma cell line RC-K8.

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Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

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Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha

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Malignant transformation of B lymphoma cell line BJAB by Epstein-Barr virus-encoded small RNAs

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Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

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Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel

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1 reference

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Relationship between REL amplification, REL function, and clinical and biologic features in diffuse large B-cell lymphomas

1 reference

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1 reference

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1 reference

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1 reference

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Deletion of either C-terminal transactivation subdomain enhances the in vitro transforming activity of human transcription factor REL in chicken spleen cells

1 reference

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Mutations of tumor necrosis factor alpha-responsive serine residues within the C-terminal transactivation domain of human transcription factor REL enhance its in vitro transforming ability

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.74

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1 reference

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1 reference

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1 reference

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31 March 2020

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10.1038/ONC.2009.74

1 reference

Europe PubMed Central

28 July 2017

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1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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