(Q33564100)

28 July 2017

The induction of folding cooperativity by ligand binding drives the allosteric response of tetracycline repressor (English)

1 reference

28 July 2017

1 reference

1 reference

Zhou Yu

2

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author name string

Sean E Reichheld

series ordinal

1

1 reference

PubMed ID

20080791

28 July 2017

Alan R Davidson

series ordinal

3

1 reference

PubMed ID

20080791

28 July 2017

language of work or name

English

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publication date

22 December 2009

1 reference

28 July 2017

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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28 July 2017

106

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28 July 2017

22263-22268

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28 July 2017

52

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A protein functional leap: how a single mutation reverses the function of the transcription regulator TetR

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Allostery: absence of a change in shape does not imply that allostery is not at play

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Dynamically driven protein allostery.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The changing landscape of protein allostery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The TetR family of transcriptional repressors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Allosteric mechanisms of signal transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The response of internal dynamics to hydrophobic core mutations in the SH3 domain from the Fyn tyrosine kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Two mutations in the tetracycline repressor change the inducer anhydrotetracycline to a corepressor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The role of dynamics in allosteric regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The relationship between conservation, thermodynamic stability, and function in the SH3 domain hydrophobic core

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The linkage between protein folding and functional cooperativity: two sides of the same coin?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Solvent-exposed residues in the Tet repressor (TetR) four-helix bundle contribute to subunit recognition and dimer stability.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Conformational changes of the Tet repressor induced by tetracycline trapping

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Combinations of the alpha-helix-turn-alpha-helix motif of TetR with respective residues from LacI or 434Cro: DNA recognition, inducer binding, and urea-dependent denaturation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Sequence determinants of folding and stability for the P22 Arc repressor dimer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Noninducible Tet repressor mutations map from the operator binding motif to the C terminus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

Transcriptional activation by tetracyclines in mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799725

The Tetracycline Repressor-A Paradigm for a Biological Switch

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911566106

Activity reversal of Tet repressor caused by single amino acid exchanges

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911566106

Structure-based design of Tet repressor to optimize a new inducer specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911566106

Tet repressor mutants with altered effector binding and allostery

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911566106

Identification of a stability determinant on the edge of the Tet repressor four-helix bundle dimerization motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911566106

Thermodynamic analysis of tetracycline-mediated induction of Tet repressor by a quantitative methylation protection assay

21 January 2018

1 reference

12 December 2020

Two-way interdomain signal transduction in tetracycline repressor

1 reference

12 December 2020

Allostery without conformational change. A plausible model

1 reference

12 December 2020

Characterization of non-inducible Tet repressor mutants suggests conformational changes necessary for induction

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0911566106

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference

PubMed ID

20080791