(Q35180176)

7 August 2017

1 reference

title

Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes (English)

1 reference

7 August 2017

1 reference

1

Christian Berens

1 reference

7 August 2017

2

Wolfgang Hillen

1 reference

PubMed ID

12869186

7 August 2017

language of work or name

English

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publication date

1 August 2003

1 reference

7 August 2017

1 reference

7 August 2017

270

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7 August 2017

3109-3121

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7 August 2017

15

1 reference

Stoichiometry of metal-tetracycline/H+antiport mediated by transposon Tn10-encoded tetracycline resistance protein inEscherichia coli

7 August 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

TetZ, a new tetracycline resistance determinant discovered in gram-positive bacteria, shows high homology to gram-negative regulated efflux systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

The 27.8-kb R-plasmid pTET3 from Corynebacterium glutamicum encodes the aminoglycoside adenyltransferase gene cassette aadA9 and the regulated tetracycline efflux system Tet 33 flanked by active copies of the widespread insertion sequence IS6100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Conformational changes of the Tet repressor induced by tetracycline trapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline-chelated Mg2+ ion initiates helix unwinding in Tet repressor induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

The Tetracycline Repressor-A Paradigm for a Biological Switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Observing conformational and activity changes of tet repressor in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Conformational changes necessary for gene regulation by Tet repressor assayed by reversible disulfide bond formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Trp scanning analysis of Tet repressor reveals conformational changes associated with operator and anhydrotetracycline binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Mechanism of Tet repressor induction by tetracyclines: length compensates for sequence in the alpha8-alpha9 loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline diffusion through phospholipid bilayers and binding to phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Enhanced antiparasitic activity of lipophilic tetracyclines: role of uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Delta pH-dependent accumulation of tetracycline in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Penetration of lipophilic agents with multiple protonation sites into bacterial cells: tetracyclines and fluoroquinolones as examples

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Inducible gene expression in mammalian cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Diverse strategies for tetracycline-regulated inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tet B or not tet B: advances in tetracycline-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

The impact of mammalian gene regulation concepts on functional genomic research, metabolic engineering, and advanced gene therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Conditional control of gene expression in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

The ons and offs of inducible transgenic technology: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Studying gene function in eukaryotes by conditional gene inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Conditional mouse models of sporadic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline regulated gene expression in Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Establishment of a system for conditional gene expression using an inducible tRNA suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Regulated expression of plant tRNA genes by the prokaryotic tet and lac repressors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Control of the functional activity of an antisense RNA by a tetracycline-responsive derivative of the human U6 snRNA promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Gene silencing in mammals by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline-controlled gene expression in Entamoeba histolytica

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

A tetracycline-inducible gene expression system in Entamoeba histolytica

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Development of a tetracycline controlled gene expression system in the parasitic protozoan Giardia lamblia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

The p65 domain from NF-kappaB is an efficient human activator in the tetracycline-regulatable gene expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Optimization and direct comparison of the dimerizer and reverse tet transcriptional control systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline-reversible silencing of eukaryotic promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

An activator/repressor dual system allows tight tetracycline-regulated gene expression in budding yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Cell-type specificity of short-range transcriptional repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Control of memory formation through regulated expression of a CaMKII transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Inducible gene knockouts in the small intestinal and colonic epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Adaptable doxycycline-regulated gene expression systems for Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline-inducible systems for Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

The responsiveness of a tetracycline-sensitive expression system differs in different cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

A novel tetracycline-dependent expression vector with low basal expression and potent regulatory properties in various mammalian cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Conditional cell ablation by stringent tetracycline-dependent regulation of barnase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Silencing of gene expression: implications for design of retrovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Use of the human EF-1alpha promoter for expression can significantly increase success in establishing stable cell lines with consistent expression: a study using the tetracycline-inducible system in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Rapid selection of tetracycline-controlled inducible cell lines using a green fluorescent-transactivator fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Evaluation of Tet-on system to avoid transgene down-regulation in ex vivo gene transfer to the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Protein-specific cervical antibody responses to primary genital herpes simplex virus type 2 infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Herpes simplex virus type 1 glycoproteins gB, gC and gD are major targets for CD4 T-lymphocyte cytotoxicity in HLA-DR expressing human epidermal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Long-term, noninvasive imaging of regulated gene expression in living mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline-regulatable factors with distinct dimerization domains allow reversible growth inhibition by p16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Bi-directional gene switching with the tetracycline repressor and a novel tetracycline antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Differential Top10 promoter regulation by six tetracycline analogues in plant cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline-inducible expression systems with reduced basal activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Determinants of protein-protein recognition by four helix bundles: changing the dimerization specificity of Tet repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Use of an internal ribosome entry site for bicistronic expression of Cre recombinase or rtTA transactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: application to interleukin 10 therapy in experimental arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Cell signaling can direct either binary or graded transcriptional responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Graded transcriptional response to different concentrations of a single transactivator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Depletion of the squalene synthase (ERG9) gene does not impair growth of Candida glabrata in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Characterisation of the growth and differentiation in vivo and in vitro-of bloodstream-form Trypanosoma brucei strain TREU 927.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

In vitro and in vivo effects of 14alpha-demethylase (ERG11) depletion in Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Conditional lineage ablation to model human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Regulated expression of the Shiga toxin B gene induces apoptosis in mammalian fibroblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Stringent doxycycline dependent control of CRE recombinase in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

The tetracycline-responsive promoter contains functional interferon-inducible response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Insect population control using a dominant, repressible, lethal genetic system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

A transgene-based, embryo-specific lethality system for insect pest management

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Modifying gene expression programs by altering core promoter chromatin architecture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Permeation of tetracyclines through membranes of liposomes and Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Negative effect of the transcriptional activator GAL4

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03694.X

Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.7792603

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1073/PNAS.89.12.5547

Identifiers

DOI

10.1046/J.1432-1033.2003.03694.X

1 reference

7 August 2017

1 reference

PubMed ID

12869186