(Q33565675)

28 July 2017

1 reference

title

Embryonic stem cell application in drug discovery (English)

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28 July 2017

1 reference

Yi-jia Lou

1

1 reference

28 July 2017

Xing-guang Liang

series ordinal

2

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28 July 2017

publication date

10 January 2011

1 reference

Acta Pharmacologica Sinica

28 July 2017

published in

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28 July 2017

volume

32

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28 July 2017

issue

2

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28 July 2017

page(s)

152-159

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Novel regulators of stem cell fates identified by a multivariate phenotype screen of small compounds on human embryonic stem cell colonies

28 July 2017

cites work

1 reference

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21 June 2018

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Decrease of intracellular pH as possible mechanism of embryotoxicity of glycol ether alkoxyacetic acid metabolites.

21 June 2018

1 reference

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High-throughput screening in embryonic stem cell-derived neurons identifies potentiators of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type glutamate receptors

21 June 2018

1 reference

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Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis

21 June 2018

1 reference

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Efficient integration of transgenes into a defined locus in human embryonic stem cells

21 June 2018

1 reference

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Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells

21 June 2018

1 reference

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Integration of statistical modeling and high-content microscopy to systematically investigate cell-substrate interactions.

21 June 2018

1 reference

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ReProGlo: a new stem cell-based reporter assay aimed to predict embryotoxic potential of drugs and chemicals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Controlling destiny through chemistry: small-molecule regulators of cell fate

21 June 2018

1 reference

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Genome modification in human embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Small molecules for stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Human embryonic stem cell technologies and drug discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Human ESC-derived neural rosettes and neural stem cell progression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Enrichment of hepatocyte-like cells with upregulated metabolic and differentiated function derived from embryonic stem cells using S-NitrosoAcetylPenicillamine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

MAPEG expression in mouse embryonic stem cell-derived hepatic tissue system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Evaluation of the embryotoxic potency of compounds in a newly revised high throughput embryonic stem cell test

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

A chemical approach to stem-cell biology and regenerative medicine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Wnt signaling and stem cell control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Coupled global and targeted proteomics of human embryonic stem cells during induced differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Differentiated fibroblastic progenies of human embryonic stem cells for toxicology screening.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

beta(1)- and beta(2)-adrenoceptor responses in cardiomyocytes derived from human embryonic stem cells: comparison with failing and non-failing adult human heart

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Derive and conquer: sourcing and differentiating stem cells for therapeutic applications.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Quantitative proteomics analysis demonstrates post-transcriptional regulation of embryonic stem cell differentiation to hematopoiesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Embryotoxicity hazard assessment of methylmercury and chromium using embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Niche-mediated control of human embryonic stem cell self-renewal and differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

A small-molecule antagonist of the hedgehog signaling pathway.

21 June 2018

1 reference

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A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

An in vitro embryotoxicity assay based on the disturbance of the differentiation of murine embryonic stem cells into endothelial cells. II. Testing of compounds.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Evaluating drug efficacy and toxicology in three dimensions: using synthetic extracellular matrices in drug discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

The potential of high-content high-throughput microscopy in drug discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Nanog and transcriptional networks in embryonic stem cell pluripotency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

A molecular basis for human embryonic stem cell pluripotency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Self-renewal of embryonic stem cells by a small molecule

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

The human embryonic stem cell-derived cardiomyocyte as a pharmacological model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Stem cell neural differentiation: A model for chemical biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Icariin-mediated expression of cardiac genes and modulation of nitric oxide signaling pathway during differentiation of mouse embryonic stem cells into cardiomyocytes in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Focal adhesion kinase signaling regulates cardiogenesis of embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Small molecules that induce cardiomyogenesis in embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009932

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Efficient differentiation of functional hepatocytes from human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Inducible effects of icariin, icaritin, and desmethylicaritin on directional differentiation of embryonic stem cells into cardiomyocytes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Neural differentiation of mouse embryonic stem cells in chemically defined medium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Crucial roles of mesodermal cell lineages in a murine embryonic stem cell-derived in vitro liver organogenesis system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Electron microscopy reveals the presence of viruses in mouse embryonic fibroblasts but neither in human embryonic fibroblasts nor in human mesenchymal cells used for hESC maintenance: toward an implementation of microbiological quality assurance pro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Embryonic stem cell test remastered: comparison between the validated EST and the new molecular FACS-EST for assessing developmental toxicity in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

An abbreviated protocol for multilineage neural differentiation of murine embryonic stem cells and its perturbation by methyl mercury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

Functional hepatocyte-like cells derived from mouse embryonic stem cells: a novel in vitro hepatotoxicity model for drug screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2010.194

A hierarchical network controls protein translation during murine embryonic stem cell self-renewal and differentiation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21217770

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Human stem cells and drug screening: opportunities and challenges

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21217770

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/APS.2010.194

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference