(Q33566736)

28 July 2017

title

Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. (English)

1 reference

28 July 2017

1 reference

1 reference

Jun Zhou

10

0 references

Min Liu

9

object named as

Min Liu

1 reference

28 July 2017

Xiao-dong Sun

1

1 reference

28 July 2017

Xing-juan Shi

2

1 reference

28 July 2017

Xiao-ou Sun

3

1 reference

28 July 2017

You-guang Luo

4

1 reference

28 July 2017

Xiao-jing Wu

5

1 reference

28 July 2017

Chang-fu Yao

6

1 reference

28 July 2017

Hai-yang Yu

7

1 reference

28 July 2017

Deng-wen Li

8

1 reference

28 July 2017

language of work or name

1 reference

10 October 2011

1 reference

Acta Pharmacologica Sinica

28 July 2017

published in

1 reference

28 July 2017

volume

32

1 reference

28 July 2017

issue

12

1 reference

28 July 2017

page(s)

1543-1548

1 reference

https://scigraph.springernature.com/pub.10.1038/aps.2011.130

28 July 2017

exact match

0 references

cites work

Cancer statistics, 2009

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Parkin regulates Eg5 expression by Hsp70 ubiquitination-dependent inactivation of c-Jun NH2-terminal kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Validating the mitotic kinesin Eg5 as a therapeutic target in pancreatic cancer cells and tumor xenografts using a specific inhibitor.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Effects of Eg5 knockdown on human prostate cancer xenograft growth and chemosensitivity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Biology and management of pancreatic cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

To step or not to step? How biochemistry and mechanics influence processivity in Kinesin and Eg5.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Genetics and biology of pancreatic ductal adenocarcinoma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Antitumor activity of a kinesin inhibitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

HR22C16: a potent small-molecule probe for the dynamics of cell division

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Kinetics: a tool to study molecular motors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Structure-based design and combinatorial chemistry yield low nanomolar inhibitors of cathepsin D.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Establishment of a continuous tumor-cell line (PANC-1) from a human carcinoma of the exocrine pancreas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010204

Ectopic expression of the microtubule-dependent motor protein Eg5 promotes pancreatic tumourigenesis

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.130

Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.130

Myosin IIA regulates cell motility and actomyosin–microtubule crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.130

Overexpression of Eg5 causes genomic instability and tumor formation in mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21986572

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A new approach to managing intraductal papillary mucinous pancreatic neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.130

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/APS.2011.130

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference