(Q33572264)

28 July 2017

title

SENP5 mediates breast cancer invasion via a TGFβRI SUMOylation cascade (English)

1 reference

28 July 2017

1 reference

1 reference

Rivki Cashman

1

1 reference

28 July 2017

Helit Cohen

2

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28 July 2017

Rotem Ben-Hamo

3

1 reference

28 July 2017

Alona Zilberberg

4

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28 July 2017

Sol Efroni

5

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28 July 2017

language of work or name

English

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publication date

1 February 2014

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28 July 2017

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28 July 2017

volume

5

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28 July 2017

issue

4

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28 July 2017

page(s)

1071-1082

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describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4011584/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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21 June 2018

1 reference

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SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression

21 June 2018

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The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system

21 June 2018

1 reference

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SUMOylation and deSUMOylation at a glance

21 June 2018

1 reference

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Emerging roles of desumoylating enzymes

21 June 2018

1 reference

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21 June 2018

1 reference

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The type I TGF-beta receptor is covalently modified and regulated by sumoylation

21 June 2018

1 reference

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Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family

21 June 2018

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Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs

21 June 2018

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21 June 2018

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Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

21 June 2018

1 reference

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ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells

21 June 2018

1 reference

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Ubiquitin-dependent regulation of TGFbeta signaling in cancer

21 June 2018

1 reference

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Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes

21 June 2018

1 reference

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Determination of TGFbeta1 protein level in human primary breast cancers and its relationship with survival

21 June 2018

1 reference

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Smad transcription factors

21 June 2018

1 reference

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Specificity and versatility in tgf-beta signaling through Smads

21 June 2018

1 reference

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Breast cancer metastasis: markers and models

21 June 2018

1 reference

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The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

SUMO: a history of modification

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Breast cancer cells with inhibition of p38alpha have decreased MMP-9 activity and exhibit decreased bone metastasis in mice

21 June 2018

1 reference

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TGF-beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Protein modification by SUMO

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

SUMO: ligases, isopeptidases and nuclear pores

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

New functions for the matrix metalloproteinases in cancer progression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Molecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Evolution and function of ubiquitin-like protein-conjugation systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Ubiquitin and its kin: how close are the family ties?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Transforming growth factor-beta1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Ubch9 conjugates SUMO but not ubiquitin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

The prognostic role of TGF-β signaling pathway in breast cancer patients.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Prognostic significance of TGF beta 1 and TGF beta 3 in human breast carcinoma.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011584

Elevated plasma levels of transforming growth factor-beta 1 (TGF-beta 1) in patients with advanced breast cancer: association with disease progression

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24658161

12 December 2020

inferred from PubMed ID database lookup

Serum levels of transforming growth factor beta1 in patients with breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24658161

12 December 2020

inferred from PubMed ID database lookup

Autocrine TGF-beta-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24658161

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.18632/ONCOTARGET.1783

0 references

PMC publication ID

4011584

1 reference

28 July 2017

1 reference