(Q33578405)

28 July 2017

title

Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation (English)

1 reference

28 July 2017

1 reference

Gabor Mocz

4

0 references

Dirk Geerts

object named as

Dirk Geerts

2

0 references

Jan Koster

object named as

Jan Koster

5

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author name string

Ingo Lange

1

1 reference

28 July 2017

David J Feith

3

1 reference

28 July 2017

André S Bachmann

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

1 October 2013

1 reference

Journal of Molecular Biology

28 July 2017

published in

1 reference

28 July 2017

volume

426

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28 July 2017

issue

2

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28 July 2017

page(s)

332-346

1 reference

AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport

28 July 2017

cites work

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DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27Kip1 activity in neuroblastoma

21 June 2018

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21 June 2018

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PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma

21 June 2018

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Determinants of the differential antizyme-binding affinity of ornithine decarboxylase

21 June 2018

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21 June 2018

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Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease

21 June 2018

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Critical factors governing the difference in antizyme-binding affinities between human ornithine decarboxylase and antizyme inhibitor.

21 June 2018

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Polyamine pathway contributes to the pathogenesis of Parkinson disease

21 June 2018

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A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

21 June 2018

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21 June 2018

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The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification

21 June 2018

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Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma

21 June 2018

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21 June 2018

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Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma

21 June 2018

1 reference

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Docking of antizyme to ornithine decarboxylase and antizyme inhibitor using experimental mutant and double-mutant cycle data

21 June 2018

1 reference

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Subcellular localization of antizyme inhibitor 2 in mammalian cells: Influence of intrinsic sequences and interaction with antizymes

21 June 2018

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Antizyme and antizyme inhibitor, a regulatory tango

21 June 2018

1 reference

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Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma

21 June 2018

1 reference

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Ornithine decarboxylase inhibition by alpha-difluoromethylornithine activates opposing signaling pathways via phosphorylation of both Akt/protein kinase B and p27Kip1 in neuroblastoma

21 June 2018

1 reference

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ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma

21 June 2018

1 reference

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21 June 2018

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Expression profile of PRAF2 in the human brain and enrichment in synaptic vesicles

21 June 2018

1 reference

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Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma

21 June 2018

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Expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in neuroblastoma: correlation with clinical features, cellular localization, and cerulenin-mediated apoptosis regulation

21 June 2018

1 reference

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Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases

21 June 2018

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Polyamines and neoplastic growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Antizyme inhibitor: mysterious modulator of cell proliferation

21 June 2018

1 reference

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21 June 2018

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Regulation of ornithine decarboxylase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

The antizyme family: polyamines and beyond

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Key role for p27Kip1, retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest in MYCN-amplified human neuroblastoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Polyamines and cancer: old molecules, new understanding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Statistics review 12: survival analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

A protein interaction map of Drosophila melanogaster

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

The MYCN oncoprotein as a drug development target

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Decarboxylases involved in polyamine biosynthesis and their inactivation by nitric oxide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Neuroblastoma: biological insights into a clinical enigma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Antizyme, a mediator of ubiquitin-independent proteasomal degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Regulation of cellular polyamines by antizyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Molecular surface recognition: determination of geometric fit between proteins and their ligands by correlation techniques

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Ornithine decarboxylase activity is critical for cell transformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

A homozygous frameshift mutation of sepiapterin reductase gene causing parkinsonism with onset in childhood.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Recent advances in neuroblastoma

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

The role of polyamines in human cancer: prospects for drug combination therapies.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Optimal docking area: a new method for predicting protein-protein interaction sites

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013099

Assay of mammalian ornithine decarboxylase activity using [14C]ornithine

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24096079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transcriptional regulation of the ornithine decarboxylase gene by c-Myc/Max/Mad network and retinoblastoma protein interacting with c-Myc

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24096079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JMB.2013.09.037

1 reference

28 July 2017

1 reference

28 July 2017

1 reference