(Q33581938)

28 July 2017

Integrin alphaIIbbeta3 activation in Chinese hamster ovary cells and platelets increases clustering rather than affinity (English)

1 reference

28 July 2017

Thomas A Bunch

1

1 reference

PubMed ID

19917607

28 July 2017

language of work or name

English

0 references

publication date

16 November 2009

1 reference

28 July 2017

9

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

28 July 2017

285

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28 July 2017

3

1 reference

28 July 2017

1841-1849

1 reference

PubMed ID

19917607

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2804342/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Structural basis for the autoinhibition of talin in regulating integrin activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Differences in regulation of Drosophila and vertebrate integrin affinity by talin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Structural basis of integrin regulation and signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Genetic, biochemical and structural approaches to talin function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Functional and structural correlations of individual alphaIIbbeta3 molecules

28 July 2018

1 reference

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Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster

28 July 2018

1 reference

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Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

28 July 2018

1 reference

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Talin is essential for integrin function in Drosophila

28 July 2018

1 reference

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Integrins: bidirectional, allosteric signaling machines

28 July 2018

1 reference

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The phosphotyrosine binding-like domain of talin activates integrins

28 July 2018

1 reference

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Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization

28 July 2018

1 reference

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Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3

28 July 2018

1 reference

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The platelet cytoskeleton stabilizes the interaction between alphaIIbbeta3 and its ligand and induces selective movements of ligand-occupied integrin.

28 July 2018

1 reference

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Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

28 July 2018

1 reference

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Determinants of specificity of a baculovirus-expressed antibody Fab fragment that binds selectively to the activated form of integrin alpha IIb beta 3.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Integrin cytoplasmic domains mediate inside-out signal transduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Platelet glycoprotein IIb-IIIa (alpha IIb beta 3 integrin) confers fibrinogen- and activation-dependent aggregation on heterologous cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804342

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

Detection of integrin alpha IIbbeta 3 clustering in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

Amino acid changes in Drosophila alphaPS2betaPS integrins that affect ligand affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

Talin is required for integrin-mediated platelet function in hemostasis and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057349

21 January 2018

1 reference

12 December 2020

Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation

1 reference

12 December 2020

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation

1 reference

12 December 2020

alpha IIb beta 3 redistribution triggered by receptor cross-linking

1 reference

12 December 2020

Maintenance of GPIIb-IIIa avidity supporting "irreversible" fibrinogen binding is energy-dependent

1 reference

12 December 2020

A novel flow-cytometry-based assay for quantification of affinity and avidity changes of integrins

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.057349

1 reference

28 July 2017

1 reference

28 July 2017

1 reference

PubMed ID

19917607