(Q33583109)

28 July 2017

title

Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry (English)

1 reference

28 July 2017

Ruth Brenk

4

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Dominic J Campopiano

object named as

Dominic J Campopiano

5

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author name string

Venugopal T Bhat

1

1 reference

28 July 2017

Anne M Caniard

2

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28 July 2017

Torsten Luksch

3

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28 July 2017

Michael F Greaney

6

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28 July 2017

publication date

16 May 2010

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28 July 2017

number of pages

8

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inferred from page(s)

published in

Nature Chemistry

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28 July 2017

volume

2

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28 July 2017

issue

6

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28 July 2017

page(s)

490-497

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The rise of fragment-based drug discovery

28 July 2017

cites work

1 reference

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A Fragment-Based Approach to Probing Adenosine Recognition Sites by Using Dynamic Combinatorial Chemistry

21 June 2018

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Structural and functional evolution of a library of constitutional dynamic polymers driven by alkali metal ion recognition

21 June 2018

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Molecular recognition and self-assembly special feature: Dynamic combinatorial synthesis of a catenane based on donor-acceptor interactions in water

21 June 2018

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Rapid oxime and hydrazone ligations with aromatic aldehydes for biomolecular labeling

21 June 2018

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Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA-MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1).

21 June 2018

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Target-driven selection in a dynamic nitrone library

21 June 2018

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Two-vial, LC-MS identification of ephedrine receptors from a solution-phase dynamic combinatorial library of over 9000 components

21 June 2018

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Self-duplicating amplification in a dynamic combinatorial library

21 June 2018

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21 June 2018

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Dynamic combinatorial chemistry: on the road to fulfilling the promise

21 June 2018

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Identification of a selective small-molecule ligand for HIV-1 frameshift-inducing stem-loop RNA from an 11,325 member resin bound dynamic combinatorial library

21 June 2018

1 reference

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Dynamic combinatorial libraries of hydrazone-linked pseudo-peptides: dependence of diversity on building block structure and chirality

21 June 2018

1 reference

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Discovery of glutathione S-transferase inhibitors using dynamic combinatorial chemistry

21 June 2018

1 reference

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Direct screening of a dynamic combinatorial library using mass spectrometry

21 June 2018

1 reference

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Design of potent inhibitors for Schistosoma japonica glutathione S-transferase

21 June 2018

1 reference

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Amplification of bifunctional ligands for calmodulin from a dynamic combinatorial library

21 June 2018

1 reference

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21 June 2018

Glutathione transferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

The chemistry and biology of inhibitors and pro-drugs targeted to glutathione S-transferases

21 June 2018

1 reference

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Amplification of acetylcholine-binding catenanes from dynamic combinatorial libraries.

21 June 2018

1 reference

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Reversible Michael addition of thiols as a new tool for dynamic combinatorial chemistry

21 June 2018

1 reference

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Molecular borromean rings

21 June 2018

1 reference

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Pseudodynamic combinatorial libraries: a receptor-assisted approach for drug discovery

21 June 2018

1 reference

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Generation of bis-cationic heterocyclic inhibitors of Bacillus subtilis HPr kinase/phosphatase from a ditopic dynamic combinatorial library

21 June 2018

1 reference

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Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase from Schistosoma japonicum

21 June 2018

1 reference

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Dynamic covalent chemistry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

Simultaneous selection, amplification and isolation of a pseudo-peptide receptor by an immobilised N-methyl ammonium ion template

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

Target-induced formation of neuraminidase inhibitors from in vitro virtual combinatorial libraries

21 June 2018

1 reference

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Dynamic deconvolution of a pre-equilibrated dynamic combinatorial library of acetylcholinesterase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

In situ generation and screening of a dynamic combinatorial carbohydrate library against concanavalin A.

21 June 2018

1 reference

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A new cyclic pseudopeptide receptor for Li+ from a dynamic combinatorial library

21 June 2018

1 reference

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Site-directed ligand discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

Virtual combinatorial libraries: dynamic generation of molecular and supramolecular diversity by self-assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

Glutathione-associated enzymes in anticancer drug resistance.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913121

Nucleophilic catalysis of hydrazone formation and transimination: implications for dynamic covalent chemistry

21 June 2018

1 reference

Orthogonal or simultaneous use of disulfide and hydrazone exchange in dynamic covalent chemistry in aqueous solution

21 January 2018

1 reference

Overcoming the drug resistance in breast cancer cells by rational design of efficient glutathione S-transferase inhibitors.

21 January 2018

1 reference

Novel class of bivalent glutathione S-transferase inhibitors

21 January 2018

1 reference

Crystallographic and thermodynamic analysis of the binding of S-octylglutathione to the Tyr 7 to Phe mutant of glutathione S-transferase from Schistosoma japonicum.

21 January 2018

1 reference

Use of Relibase for retrieving complex three-dimensional interaction patterns including crystallographic packing effects

21 January 2018

1 reference

MAB, a generally applicable molecular force field for structure modelling in medicinal chemistry.

21 January 2018

1 reference

Dynamic Combinatorial Chemistry

21 January 2018

1 reference

Dynamic combinatorial chemistry: lysozyme selects an aromatic motif that mimics a carbohydrate residue

21 January 2018

1 reference

12 December 2020

Systems chemistry: kinetic and computational analysis of a nearly exponential organic replicator

1 reference

12 December 2020

Templated amplification of an unexpected receptor for C70

1 reference

12 December 2020

A simple synthetic replicator amplifies itself from a dynamic reagent pool

1 reference

12 December 2020

Dynamic combinatorial evolution within self-replicating supramolecular assemblies

1 reference

12 December 2020

Hierarchical functional gradients of pH-responsive self-assembled monolayers using dynamic covalent chemistry on surfaces

1 reference

12 December 2020

Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEM.658

1 reference

Dimensions Publication ID

28 July 2017

0 references

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28 July 2017

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