(Q33588238)

28 July 2017

title

Neuroprotective effects of calmodulin peptide 76-121aa: disruption of calmodulin binding to mutant huntingtin (English)

1 reference

28 July 2017

Nancy A Muma

3

0 references

author name string

Nichole L Dudek

series ordinal

1

1 reference

28 July 2017

Ying Dai

series ordinal

2

1 reference

28 July 2017

publication date

10 March 2009

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28 July 2017

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28 July 2017

volume

20

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28 July 2017

issue

1

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28 July 2017

page(s)

176-189

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Protective effects of interrupting the binding of calmodulin to mutant huntingtin.

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3.

21 June 2018

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Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.

21 June 2018

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HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons

21 June 2018

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Huntingtin-protein interactions and the pathogenesis of Huntington's disease

21 June 2018

1 reference

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Calmodulin regulates transglutaminase 2 cross-linking of huntingtin.

21 June 2018

1 reference

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The hunt for huntingtin function: interaction partners tell many different stories

21 June 2018

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Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

21 June 2018

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Transglutaminase cross-links in intranuclear inclusions in Huntington disease

21 June 2018

1 reference

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Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

21 June 2018

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Molecular cloning, bacterial expression and properties of Rab31 and Rab32.

21 June 2018

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Evidence for a role for transglutaminase in Huntington's disease and the potential therapeutic implications

21 June 2018

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Small proteins that modulate calmodulin-dependent signal transduction: effects of PEP-19, neuromodulin, and neurogranin on enzyme activation and cellular homeostasis

21 June 2018

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Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells

21 June 2018

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Formic acid dissolves aggregates of an N-terminal huntingtin fragment containing an expanded polyglutamine tract: applying to quantification of protein components of the aggregates

21 June 2018

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Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity

21 June 2018

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Elevated transglutaminase-induced bonds in PHF tau in Alzheimer's disease.

21 June 2018

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Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Pathogenesis of inclusion bodies in (CAG)n/Qn-expansion diseases with special reference to the role of tissue transglutaminase and to selective vulnerability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

PEP-19 immunohistochemistry defines the basal ganglia and associated structures in the adult human brain, and is dramatically reduced in Huntington's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: a possible mechanism contributing to CAG-triplet diseases.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Transglutaminase activity is related to CAG repeat length in patients with Huntington's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Selection of peptide inhibitors of interactions involved in complex protein assemblies: association of the core and surface antigens of hepatitis B virus.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Neuropathological classification of Huntington's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Huntington's disease. Pathogenesis and management

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

The epsilon-(gamma-glutamyl)lysine crosslink and the catalytic role of transglutaminases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2008.00258.X

Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Characterization of Arabidopsis thaliana AtFKBP42 that is membrane-bound and interacts with Hsp90.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Therapeutic effects of cystamine in a murine model of Huntington's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Altered neuronal nitric oxide synthase expression contributes to disease progression in Huntington's disease transgenic mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Biphasic developmental changes in Ca2+/calmodulin-dependent proteins in R6/2 Huntington's disease mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: effects of L-NAME on symptom progression

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Tissue transglutaminase is increased in Huntington's disease brain

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Camstatins are peptide antagonists of calmodulin based upon a conserved structural motif in PEP-19, neurogranin, and neuromodulin.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805873

Activity-structure relationship of calmodulin antagonists, Naphthalenesulfonamide derivatives

31 October 2018

1 reference

12 December 2020

Hydrophobic interaction of the Ca2+-calmodulin complex with calmodulin antagonists. Naphthalenesulfonamide derivatives

1 reference

12 December 2020

Agonist and antagonist properties of calmodulin fragments

1 reference

12 December 2020

Catalytic properties of a calmodulin-regulated transglutaminase from human platelet and chicken gizzard

1 reference

12 December 2020

Calmodulin fragments can not activate target enzymes

1 reference

12 December 2020

The red cell membrane contains calmodulin-regulated crosslinking and proteolytic activity

1 reference

12 December 2020

Human genetic diseases due to codon reiteration: relationship to an evolutionary mechanism

1 reference

12 December 2020

Inhibition of Ca2+/calmodulin-dependent phosphatase activity by regucalcin in rat liver cytosol: involvement of calmodulin binding

1 reference

12 December 2020

Kinetics of calmodulin binding to calcineurin

1 reference

12 December 2020

10.1111/J.1750-3639.2008.00258.X

Identifiers

DOI

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28 July 2017

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28 July 2017

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