(Q33594461)

28 July 2017

title

Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control (English)

1 reference

28 July 2017

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Benigno Rodriguez

8

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Bruce D. Walker

17

object named as

Bruce D Walker

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28 July 2017

2

Florencia Pereyra

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28 July 2017

16

Rupert Kaul

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28 July 2017

3

Martha Nason

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28 July 2017

18

Michael R Betts

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28 July 2017

Adam R Hersperger

1

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28 July 2017

Korey Demers

4

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28 July 2017

Prameet Sheth

5

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28 July 2017

Lucy Y Shin

6

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28 July 2017

Colin M Kovacs

7

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28 July 2017

Scott F Sieg

9

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28 July 2017

Leia Teixeira-Johnson

10

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28 July 2017

Debbie Gudonis

11

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28 July 2017

Paul A Goepfert

12

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28 July 2017

Michael M Lederman

13

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28 July 2017

Ian Frank

14

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28 July 2017

George Makedonas

15

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28 July 2017

publication date

27 May 2010

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28 July 2017

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28 July 2017

volume

6

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28 July 2017

issue

5

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28 July 2017

page(s)

e1000917

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Creative Commons CC0 License

28 July 2017

copyright license

start time

27 May 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells

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Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells

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Defective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy.

21 June 2018

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Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses

21 June 2018

1 reference

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Rapid up-regulation and granule-independent transport of perforin to the immunological synapse define a novel mechanism of antigen-specific CD8+ T cell cytotoxic activity.

21 June 2018

1 reference

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21 June 2018

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Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

21 June 2018

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Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control

21 June 2018

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Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control

21 June 2018

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21 June 2018

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The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression

21 June 2018

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HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control

21 June 2018

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21 June 2018

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Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy

21 June 2018

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Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

21 June 2018

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Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy

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Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

21 June 2018

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HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype

21 June 2018

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Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes

21 June 2018

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Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection

21 June 2018

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

21 June 2018

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Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.

21 June 2018

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877741

Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877741

HIV controllers: a homogeneous group of HIV-1-infected patients with spontaneous control of viral replication

21 June 2018

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HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.

21 June 2018

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HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity

21 June 2018

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Lymphocyte-mediated cytotoxicity.

21 June 2018

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Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877741

Functional heterogeneity of cytokines and cytolytic effector molecules in human CD8+ T lymphocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877741

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

21 June 2018

1 reference

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HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877741

Viral-specific cytotoxic T lymphocytes lyse human immunodeficiency virus-infected primary T lymphocytes by the granule exocytosis pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877741

A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/perforin gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877741

Plasma human immunodeficiency virus RNA below 40 Copies/mL is rare in untreated persons even in the first years of infection

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Preservation of T Cell Proliferation Restricted by Protective HLA Alleles Is Critical for Immune Control of HIV-1 Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Induction of cytotoxic granules in human memory CD8+ T cell subsets requires cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Three memory subsets of human CD8+ T cells differently expressing three cytolytic effector molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Characterisation of diverse PRF1 mutations leading to decreased natural killer cell activity in North American families with haemophagocytic lymphohistiocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Comparisons of two-part models with competitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Patterns of immune response to a vaccine or virus as measured by intracellular cytokine staining in flow cytometry: hypothesis generation and comparison of groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000917

Perforin is not co-expressed with granzyme A within cytotoxic granules in CD8 T lymphocytes present in lymphoid tissue during chronic HIV infection

21 January 2018

1 reference

12 December 2020

Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A

1 reference

12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

12 December 2020

Presence of HIV-1 Gag-specific IFN-gamma+IL-2+ and CD28+IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infection

1 reference

12 December 2020

Flow cytometric detection of perforin upregulation in human CD8 T cells

1 reference

12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

12 December 2020

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1000917

Identifiers

DOI

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28 July 2017

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28 July 2017

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