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Flow cytometric detection of perforin upregulation in human CD8 T cells
scientific article published on 01 November 2008
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
title
Flow cytometric detection of perforin upregulation in human CD8 T cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
main subject
flow cytometry
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author
Michael R. Betts
series ordinal
3
object named as
Michael R Betts
1 reference
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Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
author name string
Adam R Hersperger
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
George Makedonas
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
publication date
1 November 2008
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
published in
Cytometry Part A
1 reference
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Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
volume
73
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
issue
11
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
page(s)
1050-1057
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Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
cites work
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7 January 2021
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A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/perforin gene
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7 January 2021
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Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A
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7 January 2021
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Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes
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7 January 2021
based on heuristic
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A novel serine esterase expressed by cytotoxic T lymphocytes
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Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte
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7 January 2021
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Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes
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Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCYTO.A.20596
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7 January 2021
based on heuristic
inferred from DOI database lookup
Delivering the kiss of death: progress on understanding how perforin works
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1 reference
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Crossref
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7 January 2021
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Perforin gene defects in familial hemophagocytic lymphohistiocytosis.
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7 January 2021
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Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.
1 reference
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Crossref
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7 January 2021
based on heuristic
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Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.
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Crossref
reference URL
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7 January 2021
based on heuristic
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Interaction of chondroitin sulfate with perforin and granzymes of cytolytic T-cells is dependent on pH.
1 reference
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Crossref
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7 January 2021
based on heuristic
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Inactivation and proteolytic degradation of perforin within lytic granules upon neutralization of acidic pH
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of cytotoxic granules in human memory CD8+ T cell subsets requires cell cycle progression.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCYTO.A.20596
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7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional heterogeneity of cytokines and cytolytic effector molecules in human CD8+ T lymphocytes
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7 January 2021
based on heuristic
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Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
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7 January 2021
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inferred from DOI database lookup
Amine reactive dyes: an effective tool to discriminate live and dead cells in polychromatic flow cytometry.
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7 January 2021
based on heuristic
inferred from DOI database lookup
The immunological synapse of CTL contains a secretory domain and membrane bridges.
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Perturbation of vesicular traffic with the carboxylic ionophore monensin
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7 January 2021
based on heuristic
inferred from DOI database lookup
Acidification of the endocytic and exocytic pathways
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Inhibitory effect of modified bafilomycins and concanamycins on P- and V-type adenosinetriphosphatases.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Three memory subsets of human CD8+ T cells differently expressing three cytolytic effector molecules.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The lymphocyte pore-forming protein perforin is associated with granules by a pH-dependent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCYTO.A.20596
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/CYTO.A.20596
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
PubMed publication ID
18615597
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18615597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18615597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
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