(Q33595798)

28 July 2017

title

Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening (English)

1 reference

Zeineb Es-Salah-Lamoureux

28 July 2017

author

1

object named as

Zeineb Es-Salah-Lamoureux

0 references

author name string

Zeineb Es-Salah-Lamoureux

1

1 reference

28 July 2017

Robert Fougere

2

1 reference

28 July 2017

Ping Yu Xiong

3

1 reference

28 July 2017

Gail A Robertson

4

1 reference

28 July 2017

David Fedida

5

1 reference

28 July 2017

language of work or name

English

0 references

publication date

28 May 2010

1 reference

28 July 2017

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28 July 2017

volume

5

1 reference

28 July 2017

issue

5

1 reference

28 July 2017

page(s)

e10876

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

28 May 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Movement of the S4 segment in the hERG potassium channel during membrane depolarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Transfer of rolf S3-S4 linker to HERG eliminates activation gating but spares inactivation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Use of voltage clamp fluorimetry in understanding potassium channel gating: a review of Shaker fluorescence data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

hERG gating microdomains defined by S6 mutagenesis and molecular modeling.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Voltage clamp fluorimetry reveals a novel outer pore instability in a mammalian voltage-gated potassium channel.

21 June 2018

1 reference

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Voltage clamp fluorimetry studies of mammalian voltage-gated K(+) channel gating.

21 June 2018

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Closing in on the resting state of the Shaker K(+) channel.

21 June 2018

1 reference

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A direct demonstration of closed-state inactivation of K+ channels at low pH.

21 June 2018

1 reference

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Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Gating charges in the activation and inactivation processes of the HERG channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Gating currents associated with intramembrane charge displacement in HERG potassium channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Coupling between voltage sensor activation, Ca2+ binding and channel opening in large conductance (BK) potassium channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Fast and slow voltage sensor movements in HERG potassium channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Interactions between S4-S5 linker and S6 transmembrane domain modulate gating of HERG K+ channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Fluorescence quenching: A tool for single-molecule protein-folding study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

The voltage sensor in voltage-dependent ion channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Sequential gating in the human heart K(+) channel Kv1.5 incorporates Q(1) and Q(2) charge components

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Proton and zinc effects on HERG currents

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Human ether-à-go-go-related gene K+ channel gating probed with extracellular ca2+. Evidence for two distinct voltage sensors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Molecular determinants of dofetilide block of HERG K+ channels.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Characterizing voltage-dependent conformational changes in the Shaker K+ channel with fluorescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

The inward rectification mechanism of the HERG cardiac potassium channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Shaker potassium channel gating. III: Evaluation of kinetic models for activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Electrostatic interactions of S4 voltage sensor in shaker K+ channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

A distinct potassium channel polypeptide encoded by the Drosophila eag locus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Regional specificity of human ether-a'-go-go-related gene channel activation and inactivation gating.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010876

Direct physical measure of conformational rearrangement underlying potassium channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010876

Voltage-shift of the current activation in HERG S4 mutation (R534C) in LQT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010876

The pore domain outer helix contributes to both activation and inactivation of the HERG K+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010876

Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-à-go-go-related gene channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010876

Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010876

Interactions between charged residues in the transmembrane segments of the voltage-sensing domain in the hERG channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010876

Interaction simulation of hERG K+ channel with its specific BeKm-1 peptide: insights into the selectivity of molecular recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010876

Mechanism for the effects of extracellular acidification on HERG-channel function.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878317

Reconstructing voltage sensor-pore interaction from a fluorescence scan of a voltage-gated K+ channel

30 October 2018

1 reference

12 December 2020

Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels

1 reference

12 December 2020

4-aminopyridine prevents the conformational changes associated with p/c-type inactivation in shaker channels

1 reference

12 December 2020

A novel extracellular calcium sensing mechanism in voltage-gated potassium ion channels

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0010876

Identifiers

DOI

1 reference

28 July 2017

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1 reference

28 July 2017

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