(Q33597062)

28 July 2017

title

Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma (English)

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28 July 2017

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6

Wim van Criekinge

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Manon van Engeland

13

object named as

Manon van Engeland

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28 July 2017

Iris J H van Vlodrop

1

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28 July 2017

Marcella M L Baldewijns

2

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28 July 2017

Kim M Smits

3

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28 July 2017

Leo J Schouten

4

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28 July 2017

Leander van Neste

5

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28 July 2017

Wim van Criekinge

6

1 reference

28 July 2017

Hein van Poppel

7

1 reference

28 July 2017

Evelyne Lerut

8

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28 July 2017

Kornel E Schuebel

9

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28 July 2017

Nita Ahuja

10

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28 July 2017

James G Herman

11

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28 July 2017

Adriaan P de Bruïne

12

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28 July 2017

language of work or name

English

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publication date

30 December 2009

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The American Journal of Pathology

28 July 2017

published in

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28 July 2017

volume

176

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28 July 2017

issue

2

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28 July 2017

page(s)

575-584

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Genetics and epigenetics of renal cell cancer

28 July 2017

cites work

1 reference

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A human bone morphogenetic protein antagonist is down-regulated in renal cancer

14 July 2018

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High-grade clear cell renal cell carcinoma has a higher angiogenic activity than low-grade renal cell carcinoma based on histomorphological quantification and qRT-PCR mRNA expression profile

14 July 2018

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Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor

14 July 2018

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Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation

14 July 2018

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14 July 2018

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14 July 2018

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The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein

14 July 2018

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14 July 2018

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Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray

14 July 2018

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Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers

14 July 2018

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Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis

14 July 2018

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Bone morphogenetic proteins in melanoma: angel or devil?

14 July 2018

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Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from The Netherlands cohort study

14 July 2018

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Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1).

14 July 2018

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Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancer

14 July 2018

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BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells

14 July 2018

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The von Hippel-Lindau tumor suppressor gene and kidney cancer

14 July 2018

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Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis

14 July 2018

1 reference

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Bone morphogenetic protein-2 stimulates angiogenesis in developing tumors.

14 July 2018

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Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Evidence that bone morphogenetic protein 4 has multiple biological functions during kidney and urinary tract development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Gremlin: an example of the re-emergence of developmental programmes in diabetic nephropathy.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Drm/Gremlin transcriptionally activates p21(Cip1) via a novel mechanism and inhibits neoplastic transformation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Activation of the p53 tumor suppressor protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

VHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma

14 July 2018

1 reference

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BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21(CIP1) and p27(KIP1).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

DRM/GREMLIN (CKTSF1B1) maps to human chromosome 15 and is highly expressed in adult and fetal brain

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter

14 July 2018

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IHG-2, a mesangial cell gene induced by high glucose, is human gremlin. Regulation by extracellular glucose concentration, cyclic mechanical strain, and transforming growth factor-beta1

14 July 2018

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Biosynthesis, post-translation modification, and functional characterization of Drm/Gremlin

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

A mouse cerberus/Dan-related gene family

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

The Heidelberg classification of renal cell tumours.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in culture

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Bone morphogenetic proteins: multifunctional regulators of vertebrate development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Genetic and epigenetic alterations in the von hippel-lindau gene: the influence on renal cancer prognosis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

BMP4 activation and secretion are negatively regulated by an intracellular gremlin-BMP4 interaction

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene.

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Methylation-specific PCR unraveled.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808066

Renal cell carcinoma: current prognostic factors. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC).

30 October 2018

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K-ras mutations and RASSF1A promoter methylation in colorectal cancer

30 October 2018

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12 December 2020

Gremlin promotes vascular smooth muscle cell proliferation and migration

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12 December 2020

Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauci-immune glomerulonephritis

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12 December 2020

Molecular pathology of von HippelLindau disease and the VHL tumour suppressor gene

1 reference

12 December 2020

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning

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12 December 2020

Bone morphogenetic protein-2 blocks MDA MB 231 human breast cancer cell proliferation by inhibiting cyclin-dependent kinase-mediated retinoblastoma protein phosphorylation

1 reference

12 December 2020

A large-scale prospective cohort study on diet and cancer in the Netherlands

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12 December 2020

10.2353/AJPATH.2010.090442

Identifiers

DOI

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28 July 2017

1 reference

28 July 2017

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