(Q33598870)

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4-Alkyloxyimino derivatives of uridine-5'-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors

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Europe PubMed Central

PubMed publication ID

28 July 2017

4-Alkyloxyimino derivatives of uridine-5'-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors (English)

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Europe PubMed Central

PubMed publication ID

28 July 2017

Kenneth A. Jacobson

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Kenneth A Jacobson

8

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P Suresh Jayasekara

1

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Europe PubMed Central

PubMed publication ID

28 July 2017

Matthew O Barrett

2

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Europe PubMed Central

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28 July 2017

Christopher B Ball

3

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Europe PubMed Central

PubMed publication ID

28 July 2017

Kyle A Brown

4

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Europe PubMed Central

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28 July 2017

Eva Hammes

5

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Europe PubMed Central

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28 July 2017

Ramachandran Balasubramanian

6

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Europe PubMed Central

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28 July 2017

T Kendall Harden

7

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Europe PubMed Central

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28 July 2017

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publication date

18 April 2014

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Europe PubMed Central

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28 July 2017

Journal of Medicinal Chemistry

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Europe PubMed Central

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28 July 2017

57

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Europe PubMed Central

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28 July 2017

9

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Europe PubMed Central

PubMed publication ID

28 July 2017

3874-3883

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

4-Alkyloxyimino-cytosine nucleotides: tethering approaches to molecular probes for the P2Y6 receptor.

1 reference

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Rapid synthesis of alkoxyamine hydrochloride derivatives from alkyl bromide and N,N'-di-tert-butoxycarbonylhydroxylamine ((Boc)2NOH).

1 reference

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14 July 2018

Bright building blocks for chemical biology

1 reference

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Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors

1 reference

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Click chemistry for drug development and diverse chemical-biology applications.

1 reference

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Apical targeting of the P2Y(4) receptor is directed by hydrophobic and basic residues in the cytoplasmic tail

1 reference

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Novel fluorescent antagonist as a molecular probe in A(3) adenosine receptor binding assays using flow cytometry

1 reference

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P2Y6 receptor signaling pathway mediates inflammatory responses induced by monosodium urate crystals

1 reference

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Pharmacological characterization of uracil nucleotide-preferring P2Y receptors modulating intestinal motility: a study on mouse ileum

1 reference

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14 July 2018

Regional expression of P2Y(4) receptors in the rat central nervous system.

1 reference

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14 July 2018

Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphate δ-ester modifications as selective agonists of the P2Y(4) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018175

14 July 2018

Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors

1 reference

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14 July 2018

P2Y nucleotide receptors: promise of therapeutic applications

1 reference

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14 July 2018

5-OMe-UDP is a potent and selective P2Y(6)-receptor agonist

1 reference

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14 July 2018

Functionalized congener approach to the design of ligands for G protein-coupled receptors (GPCRs).

1 reference

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14 July 2018

Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018175

14 July 2018

Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors.

1 reference

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14 July 2018

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

1 reference

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14 July 2018

Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors

1 reference

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14 July 2018

Purine and pyrimidine (P2) receptors as drug targets

1 reference

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14 July 2018

Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study

1 reference

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14 July 2018

ATP, an agonist at the rat P2Y(4) receptor, is an antagonist at the human P2Y(4) receptor

1 reference

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14 July 2018

Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate

1 reference

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14 July 2018

Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor

1 reference

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Suramin is a slowly-equilibrating but competitive antagonist at P2x-receptors in the rabbit isolated ear artery

1 reference

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5′-Nucleotidase: molecular structure and functional aspects

2 references

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14 July 2018

https://pubmed.ncbi.nlm.nih.gov/24712832

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Gene deletion of P2Y4 receptor lowers exercise capacity and reduces myocardial hypertrophy with swimming exercise.

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P2Y(4) nucleotide receptor: a novel actor in post-natal cardiac development.

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K+ secretion activated by luminal P2Y2 and P2Y4 receptors in mouse colon

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30 October 2018

Identifiers

10.1021/JM500367E

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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