(Q38151635)

English

Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors

scientific article published on 23 September 2013

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scholarly article

1 reference

Europe PubMed Central

29 August 2017

Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors (English)

1 reference

Europe PubMed Central

29 August 2017

author name string

Mariya al-Rashida

1

1 reference

Europe PubMed Central

29 August 2017

Jamshed Iqbal

2

1 reference

Europe PubMed Central

29 August 2017

publication date

23 September 2013

1 reference

Europe PubMed Central

29 August 2017

Medicinal Research Reviews

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Europe PubMed Central

29 August 2017

34

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Europe PubMed Central

29 August 2017

4

1 reference

Europe PubMed Central

29 August 2017

703-743

1 reference

Europe PubMed Central

29 August 2017

Physiology and pathophysiology of purinergic neurotransmission

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Purine and pyrimidine receptors

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Purinergic signalling in neuron-glia interactions

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Impact of ectoenzymes on p2 and p1 receptor signaling.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-3

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The GDA1_CD39 superfamily: NTPDases with diverse functions

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

CD39 Is an Ecto-(Ca,Mg)-apyrase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Extracellular metabolism of ATP and other nucleotides

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

A capillary electrophoresis method for the characterization of ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) and the analysis of inhibitors by in-capillary enzymatic microreaction

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structural insight into signal conversion and inactivation by NTPDase2 in purinergic signaling

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystallographic evidence for a domain motion in rat nucleoside triphosphate diphosphohydrolase (NTPDase) 1

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structural insight into activation mechanism of Toxoplasma gondii nucleoside triphosphate diphosphohydrolases by disulfide reduction

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystallization and preliminary X-ray structural analysis of nucleoside triphosphate hydrolases from Neospora caninum and Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Distribution of NTPDase5 and NTPDase6 and the regulation of P2Y receptor signalling in the rat cochlea

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystallographic snapshots along the reaction pathway of nucleoside triphosphate diphosphohydrolases

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Entpd5 is essential for skeletal mineralization and regulates phosphate homeostasis in zebrafish.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

NPP-type ectophosphodiesterases: unity in diversity

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

A highly sensitive CE-UV method with dynamic coating of silica-fused capillaries for monitoring of nucleotide pyrophosphatase/phosphodiesterase reactions

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Subcellular targeting and function of osteoblast nucleotide pyrophosphatase phosphodiesterase 1.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Role of somatomedin-B-like domains on ENPP1 inhibition of insulin signaling.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Inhibition of ectonucleotidase with ARL67156 prevents the development of calcific aortic valve disease in warfarin-treated rats.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Chemical evolution of autotaxin inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Identification of p2y9/GPR23 as a Novel G Protein-coupled Receptor for Lysophosphatidic Acid, Structurally Distant from the Edg Family

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The emerging role of lysophosphatidic acid in cancer

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structural basis of substrate discrimination and integrin binding by autotaxin

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: implications for mechanism and evolution

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structure-function relationships of autotaxin, a secreted lysophospholipase D.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

A 3D view of autotaxin

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Nucleotide pyrophosphatases/phosphodiesterases on the move

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Identification of CD13, CD107a, and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-dependent upregulation

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Cellular function and molecular structure of ecto-nucleotidases.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

NPP4 is a procoagulant enzyme on the surface of vascular endothelium

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Design and synthesis of pyrazole derivatives as potent and selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Design and synthesis of selective inhibitors of placental alkaline phosphatase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The ectonucleotidases alkaline phosphatase and nucleoside triphosphate diphosphohydrolase 2 are associated with subsets of progenitor cell populations in the mouse embryonic, postnatal and adult neurogenic zones

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Ecto-5'-nucleotidase: Structure function relationships

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Mechanism of hydrolysis of phosphate esters by the dimetal center of 5'-nucleotidase based on crystal structures

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Site-directed mutagenesis of a human brain ecto-apyrase: evidence that the E-type ATPases are related to the actin/heat shock 70/sugar kinase superfamily.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Mutagenesis of apyrase conserved region 1 alters the nucleotide substrate specificity

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Cloning and characterization of the ecto-nucleotidase NTPDase3 from rat brain: Predicted secondary structure and relation to other members of the E-NTPDase family and actin

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Purification, characterization and cellular localization of 5'-nucleotidase from Torpedo electric organ

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The membrane topography of ecto-5'-nucleotidase in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Subcellular distribution and movement of 5'-nucleotidase in rat cells

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Cytochemistry of Golgi fractions prepared from rat liver

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Evidence for the translocation of 5'-nucleotidase across hepatic membranes in vivo

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystal structure of human cytosolic 5'-nucleotidase II: insights into allosteric regulation and substrate recognition

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystal structure of a human mitochondrial deoxyribonucleotidase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Active and regulatory sites of cytosolic 5'-nucleotidase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Primary structure of human placental 5'-nucleotidase and identification of the glycolipid anchor in the mature form

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Murine ecto-5'-nucleotidase (CD73): cDNA cloning and tissue distribution

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Characterization of soluble vs membrane-bound human placental 5'-nucleotidase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Biochemical and mass spectrometric characterization of soluble ecto-5'-nucleotidase from bull seminal plasma.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Release of the glycosylphosphatidylinositol-anchored enzyme ecto-5'-nucleotidase by phospholipase C: catalytic activation and modulation by the lipid bilayer

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Soluble low-Km 5'-nucleotidase from electric-ray (Torpedo marmorata) electric organ and bovine cerebral cortex is derived from the glycosyl-phosphatidylinositol-anchored ectoenzyme by phospholipase C cleavage

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystal structure of the human ecto-5'-nucleotidase (CD73): insights into the regulation of purinergic signaling

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

5′-Nucleotidase: molecular structure and functional aspects

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Evidence for Coordinated Induction and Repression of Ecto-5'-Nucleotidase (CD73) and the A2a Adenosine Receptor in a Human B Cell Line

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Ecto-5'-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

NTPDase and 5'-nucleotidase activities in physiological and disease conditions: new perspectives for human health

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Nucleoside-5'-monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-5'-nucleotidase.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+Gr1+ cells

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

CD73: a novel target for cancer immunotherapy

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Evidence for the involvement of ecto-5'-nucleotidase (CD73) in drug resistance

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Tumor-promoting functions of adenosine

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Crystal structure of a Legionella pneumophila ecto -triphosphate diphosphohydrolase, a structural and functional homolog of the eukaryotic NTPDases

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Possible effects of microbial ecto-nucleoside triphosphate diphosphohydrolases on host-pathogen interactions

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

X-ray structure of the Escherichia coli periplasmic 5'-nucleotidase containing a dimetal catalytic site

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The nucleoside triphosphate diphosphohydrolase-1/CD39 is incorporated into human immunodeficiency type 1 particles, where it remains biologically active

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases).

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Purine signaling and potential new therapeutic approach: possible outcomes of NTPDase inhibition

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Inhibition of ecto-ATPase by PPADS, suramin and reactive blue in endothelial cells, C6 glioma cells and RAW 264.7 macrophages

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

P2-receptor antagonists: IV. Blockade of P2-receptor subtypes and ecto-nucleotidases by compounds related to reactive blue 2.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Inhibition of human and mouse plasma membrane bound NTPDases by P2 receptor antagonists

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Reactive red 2: a P2y-selective purinoceptor antagonist and an inhibitor of ecto-nucleotidase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Trichomonas vaginalis nucleoside triphosphate diphosphohydrolase and ecto-5'-nucleotidase activities are inhibited by lycorine and candimine

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Inhibition of human NTPDase 2 by modification of an intramembrane cysteine by p-chloromercuriphenylsulfonate and oxidative cross-linking of the transmembrane domains.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Ecto-5'-nucleotidase/CD73 inhibition by quercetin in the human U138MG glioma cell line

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Inhibition of vascular ectonucleotidase activities by the pro-drugs ticlopidine and clopidogrel favours platelet aggregation.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

P2-purinoceptor antagonists: II. Blockade of P2-purinoceptor subtypes and ecto-nucleotidases by compounds related to Evans blue and trypan blue.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Enzyme kinetics and pharmacological characterization of nucleotidases released from the guinea pig isolated vas deferens during nerve stimulation: evidence for a soluble ecto-nucleoside triphosphate diphosphohydrolase-like ATPase and a soluble ecto-

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Physiological roles for ecto-5'-nucleotidase (CD73).

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Novel inhibitors of nucleoside triphosphate diphosphohydrolases: chemical synthesis and biochemical and pharmacological characterizations

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Adenosine nucleotides acting at the human P2Y1 receptor stimulate mitogen-activated protein kinases and induce apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

8-BuS-ATP derivatives as specific NTPDase1 inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Recent advances on polyoxometalate-based molecular and composite materials

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Decavanadate (V10 O28 6-) and oxovanadates: oxometalates with many biological activities

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Structural principles governing domain motions in proteins

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Characterization of Rat NTPDase1, -2, and -3 ectodomains refolded from bacterial inclusion bodies

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

5'-nucleotidase from bull seminal plasma, chicken gizzard and snake venom is a zinc metalloprotein

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Cobalt activation of Escherichia coli 5'-nucleotidase is due to zinc ion displacement at only one of two metal-ion-binding sites

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Cloning, sequencing, and expression of a human brain ecto-apyrase related to both the ecto-ATPases and CD39 ecto-apyrases1.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Characterization of disulfide bonds in human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3): implications for NTPDase structural modeling

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Localization of plasma membrane bound NTPDases in the murine reproductive tract.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: implications for modulation of multiple homeostatic systems including feeding and sleep-wake behaviors.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Characterization of a monoclonal antibody as the first specific inhibitor of human NTP diphosphohydrolase-3 : partial characterization of the inhibitory epitope and potential applications

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Epitope mapping in cell surface proteins by site-directed masking: defining the structural elements of NTPDase3 inhibition by a monoclonal antibody.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

An antigenic domain within a catalytically active Leishmania infantum nucleoside triphosphate diphosphohydrolase (NTPDase 1) is a target of inhibitory antibodies.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Expression of membrane-bound NPP-type ecto-phosphodiesterases in rat podocytes cultured at normal and high glucose concentrations

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The role of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP1) is correlated with astrocytic tumor grade.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Autotaxin inhibition: challenges and progress toward novel anti-cancer agents

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Optimization of a pipemidic acid autotaxin inhibitor

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Characterization of non-lipid autotaxin inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

alpha- and beta-substituted phosphonate analogs of LPA as autotaxin inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

1,3,4-Oxadiazole-2(3H)-thione and its analogues: a new class of non-competitive nucleotide pyrophosphatases/phosphodiesterases 1 inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

TNAP, TrAP, ecto-purinergic signaling, and bone remodeling

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Synthesis and evaluation of benzo[b]thiophene derivatives as inhibitors of alkaline phosphatases

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Residues determining the binding specificity of uncompetitive inhibitors to tissue-nonspecific alkaline phosphatase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Identification and characterization of novel tissue-nonspecific alkaline phosphatase inhibitors with diverse modes of action

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

The use of potent inhibitors of alkaline phosphatase to investigate the role of the enzyme in intestinal transport of inorganic phosphate

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

A model of the transition state in the alkaline phosphatase reaction

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

New oxo-bridged peroxotungsten complexes containing biogenic co-ligand as potent inhibitors of alkaline phosphatase activity

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Polyoxometalates as potent and selective inhibitors of alkaline phosphatases with profound anticancer and amoebicidal activities.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Sulfonamide inhibition of human alkaline phosphatase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Discovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Identification of novel chromone based sulfonamides as highly potent and selective inhibitors of alkaline phosphatases.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Calix[4]arene methylenebisphosphonic acids as calf intestine alkaline phosphatase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Inhibition of alkaline phosphatase activity by okadaic acid, a protein phosphatase inhibitor

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Inhibition of a cold-active alkaline phosphatase by imipenem revealed by in silico modeling of metallo-β-lactamase active sites.

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Polyoxometalates—a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Virtual Screening Identifies Novel Sulfonamide Inhibitors of ecto-5′-Nucleotidase

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Capillary electrophoresis-based nanoscale assays for monitoring ecto-5′-nucleotidase activity and inhibition in preparations of recombinant enzyme and melanoma cell membranes

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

ATPase activity and conformational changes in the regulation of actin

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Inhibition of rat synaptic membrane Na+/K+-ATPase and ecto-nucleoside triphosphate diphosphohydrolases by 12-tungstosilicic and 12-tungstophosphoric acid

1 reference

https://api.crossref.org/works/10.1002%2FMED.21302

21 January 2018

Identifiers

10.1002/MED.21302

1 reference

Europe PubMed Central

29 August 2017

1 reference

Europe PubMed Central

29 August 2017

ResearchGate publication ID

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