(Q33605213)

28 July 2017

title

Characterization of DNA damage induced by a natural product antitumor antibiotic leinamycin in human cancer cells (English)

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28 July 2017

0 references

1 reference

Velliyur Viswesh

1

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author name string

Kent Gates

series ordinal

2

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28 July 2017

Daekyu Sun

series ordinal

3

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28 July 2017

publication date

1 January 2010

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Chemical Research in Toxicology

28 July 2017

published in

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28 July 2017

volume

23

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28 July 2017

issue

1

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28 July 2017

page(s)

99-107

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describes a project that uses

28 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2810146/fullTextXML

inferred from PubMed Central ID database lookup

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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A fluorimetric assay for the spontaneous release of an N7-alkylguanine residue from duplex DNA.

30 October 2018

1 reference

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30 October 2018

1 reference

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Small molecules that mimic the thiol-triggered alkylating properties seen in the natural product leinamycin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810146

Synthesis and antitumor activity of novel C-8 ester derivatives of leinamycin

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810146

Activation of leinamycin by thiols: a theoretical study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810146

Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810146

DNA alkylation by leinamycin can be triggered by cyanide and phosphines

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810146

DC 107, a novel antitumor antibiotic produced by a Streptomyces sp

30 October 2018

1 reference

12 December 2020

Leinamycin, a new antitumor antibiotic from Streptomyces: producing organism, fermentation and isolation

1 reference

12 December 2020

DNA strand scission by the novel antitumor antibiotic leinamycin

1 reference

12 December 2020

1,2-Dithiolan-3-one 1-oxides: a class of thiol-activated DNA-cleaving agents that are structurally related to the natural product leinamycin

1 reference

12 December 2020

Thiol-independent DNA cleavage by a leinamycin degradation product

1 reference

12 December 2020

Investigating nucleic acid damage processes via independent generation of reactive intermediates

1 reference

12 December 2020

Synthesis and antitumor activity of leinamycin derivatives: modifications of C-8 hydroxy and C-9 keto groups

1 reference

12 December 2020

DNA cleavage by 7-methylbenzopentathiepin: a simple analog of the antitumor antibiotic varacin

1 reference

12 December 2020

The nature and origin of DNA single-strand breaks determined with the comet assay

1 reference

12 December 2020

Analytical and numerical techniques for evaluation of free radical damage in cultured cells using imaging cytometry and fluorescent indicators

1 reference

12 December 2020

Synthesis and antitumor activity of novel thioester derivatives of leinamycin

1 reference

12 December 2020

Antitumor activity of KF22678, a novel thioester derivative of leinamycin

1 reference

12 December 2020

Thiol-dependent DNA cleavage by 3H-1,2-benzodithiol-3-one 1,1-dioxide

1 reference

12 December 2020

Molecular Structure of a Novel Antitumor Antibiotic Leinamycin

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1246/CL.1993.1957

Identifiers

DOI

10.1021/TX900301R

1 reference

28 July 2017

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28 July 2017

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