(Q33606875)

28 July 2017

GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism (English)

1 reference

28 July 2017

Asaf Keller

4

0 references

Barbara S Slusher

series ordinal

3

object named as

Barbara S Slusher

1 reference

28 July 2017

Emilio R Garrido Sanabria

series ordinal

1

1 reference

PubMed ID

12917384

28 July 2017

Krystyna M Wozniak

series ordinal

2

1 reference

PubMed ID

12917384

28 July 2017

language of work or name

English

0 references

publication date

13 August 2003

1 reference

Journal of Neurophysiology

28 July 2017

1 reference

28 July 2017

91

1 reference

28 July 2017

1

1 reference

28 July 2017

182-193

1 reference

Short-term synaptic plasticity

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

NAAG inhibits KCl-induced [(3)H]-GABA release via mGluR3, cAMP, PKA and L-type calcium conductance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

The multifarious hippocampal mossy fiber pathway: a review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Facilitation, augmentation and potentiation at central synapses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Reciprocal interactions between CA3 network activity and strength of recurrent collateral synapses.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Induction of long-lasting depression by (+)-alpha-methyl-4-carboxyphenylglycine and other group II mGlu receptor ligands in the dentate gyrus of the hippocampus in vitro.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

N-acetylaspartylglutamate, N-acetylaspartate, and N-acetylated alpha-linked acidic dipeptidase in human brain and their alterations in Huntington and Alzheimer's diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

N-acetylaspartylglutamate stimulates metabotropic glutamate receptor 3 to regulate expression of the GABA(A) alpha6 subunit in cerebellar granule cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

The nagging question of the function of N-acetylaspartylglutamate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Heterogeneity of release probability, facilitation, and depletion at central synapses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Immunohistochemical distribution of metabotropic glutamate receptor subtypes mGluR1b, mGluR2/3, mGluR4a and mGluR5 in human hippocampus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Distinct short-term plasticity at two excitatory synapses in the hippocampus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Hippocampal circuitry complicates analysis of long-term potentiation in mossy fiber synapses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

The regional distribution of N-acetylaspartylglutamate (NAAG) and peptidase activity against NAAG in the rat nervous system.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

N-acetyl-aspartyl-glutamate (NAAG) elicits rapid increase in intraneuronal Ca2+ in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Calcium dependence of the rate of exocytosis in a synaptic terminal

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Immunocytochemical distribution of N-acetylaspartylglutamate in the rat forebrain and glutamatergic pathways.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Interactions Between N‐Acetylaspartylglutamate and AMPA, Kainate, and NMDA Binding Sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Multivesicular release from excitatory synapses of cultured hippocampal neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

A study of possible excitatory effects of N-acetylaspartylglutamate in different in vivo and in vitro brain preparations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Localization of N-acetylaspartylglutamate-like immunoreactivity in selected areas of the rat brain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Ultrastructural localization of N-acetylaspartylglutamate in synaptic vesicles of retinal neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Release of N-acetylaspartylglutamate on depolarization of rat brain slices

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Characteristics of local excitatory circuits studied with glutamate microapplication in the CA3 area of rat hippocampal slices.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Excitatory synaptic transmission in cultures of rat olfactory bulb.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Toxicity of N-acetylaspartylglutamate and its protection by NMDA and non-NMDA receptor antagonists.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Immunocytochemical localization of the N-acetyl-aspartyl-glutamate (NAAG) hydrolyzing enzyme N-acetylated alpha-linked acidic dipeptidase (NAALADase)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

N-acetylaspartylglutamate acts as an agonist upon homomeric NMDA receptor (NMDAR1) expressed in Xenopus oocytes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate

21 June 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Short-term synaptic plasticity, simulation of nerve terminal dynamics, and the effects of protein kinase C activation in rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Neuroprotective effects of N-acetylaspartylglutamate in a neonatal rat model of hypoxia-ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Dynamics of excitatory transmitter release: analysis of synaptic responses in CA3 hippocampal neurons after repetitive stimulation of afferent fibers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

N-acetylaspartylglutamate catabolism is achieved by an enzyme on the cell surface of neurons and glia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

N-acetylaspartylglutamate (NAAG) is the probable mediator of axon-to-glia signaling in the crayfish medial giant nerve fiber

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Design of NAALADase inhibitors: a novel neuroprotective strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Calcium-dependent mechanisms involved in presynaptic long-term depression at the hippocampal mossy fibre-CA3 synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Synthesis and Biological Evaluation of Thiol-Based Inhibitors of Glutamate Carboxypeptidase II: Discovery of an Orally Active GCP II Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Pharmacology of metabotropic glutamate receptors at the mossy fiber synapses of the guinea pig hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Distribution of N-acetylaspartylglutamate immunoreactivity in human brain and its alteration in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Light and electron microscopic immunohistochemical localization of N-acetylaspartylglutamate (NAAG) in the olivocerebellar pathway of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Molecular modeling of the interactions of glutamate carboxypeptidase II with its potent NAAG-based inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Synthesis and release of N-acetylaspartylglutamate (NAAG) by crayfish nerve fibers: implications for axon-glia signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

NAALADase (GCP II) inhibition prevents cocaine-kindled seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Quantal mechanism of long-term potentiation in hippocampal mossy-fiber synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

GCPII (NAALADase) inhibition prevents long-term diabetic neuropathy in type 1 diabetic BB/Wor rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00465.2003

Random response fluctuations lead to spurious paired-pulse facilitation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

In vitro binding characteristics of a new selective group II metabotropic glutamate receptor radioligand, [3H]LY354740, in rat brain.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

N-acetyl-aspartylglutamate modulation of N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat hippocampal slices.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810521

Quantal components of unitary EPSCs at the mossy fibre synapse on CA3 pyramidal cells of rat hippocampus

30 October 2018

1 reference

12 December 2020

Orientation selectivity of cortical neurons during intracellular blockade of inhibition

1 reference

12 December 2020

Comparative distribution of N-acetylaspartylglutamate and GAD67 in the cerebellum and precerebellar nuclei of the rat utilizing enhanced carbodiimide fixation and immunohistochemistry

1 reference

12 December 2020

Differential distribution of N-acetylaspartylglutamate and N-acetylaspartate immunoreactivities in rat forebrain

1 reference

12 December 2020

Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase

1 reference

12 December 2020

Presynaptic inhibition of excitatory synaptic transmission by muscarinic and metabotropic glutamate receptor activation in the hippocampus: are Ca2+ channels involved?

1 reference

12 December 2020

Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fibre synapses

1 reference

12 December 2020

N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells

1 reference

12 December 2020

Low-concentration N-acetylaspartylglutamate suppresses the climbing fiber response of Purkinje cells in guinea pig cerebellar slices and the responses to excitatory amino acids of Xenopus laevis oocytes injected with cerebellar mRNA

1 reference

12 December 2020

The effects of N-acetylated alpha-linked acidic dipeptidase (NAALADase) inhibitors on [3H]NAAG catabolism in vivo

1 reference

12 December 2020

Action of N-acetyl-aspartic and N-acetyl-aspartyl-glutamic acids on the spontaneous electrical activity of the cat cerebral cortex

1 reference

12 December 2020

High concentrations of N-acetylaspartylglutamate (NAAG) selectively activate NMDA receptors on mouse spinal cord neurons in cell culture

1 reference

12 December 2020

Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury

1 reference

12 December 2020

Blockade of NAALADase: a novel neuroprotective strategy based on limiting glutamate and elevating NAAG

1 reference

12 December 2020

N-Acetylated alpha-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin

1 reference

12 December 2020

N-acetylaspartylglutamate protects against transient focal cerebral ischemia in rats

1 reference

12 December 2020

Identifiers

DOI

10.1152/JN.00465.2003

1 reference

28 July 2017

1 reference

28 July 2017

1 reference

PubMed ID

12917384