(Q33610879)

28 July 2017

title

The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts (English)

1 reference

28 July 2017

0 references

dasatinib monohydrate

1 reference

1 reference

5

Ghanem Ghanem

1 reference

28 July 2017

3

Mehdi Najar

1 reference

28 July 2017

2

Laurence Lagneaux

1 reference

28 July 2017

Hichame Id Boufker

1

1 reference

28 July 2017

Martine Piccart

series ordinal

4

1 reference

28 July 2017

Jean-Jacques Body

series ordinal

6

1 reference

28 July 2017

Fabrice Journé

series ordinal

7

1 reference

28 July 2017

language of work or name

English

0 references

publication date

17 June 2010

1 reference

28 July 2017

1 reference

28 July 2017

volume

10

1 reference

28 July 2017

page(s)

298

1 reference

Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts.

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Effects of imatinib mesylate in osteoblastogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Src as a therapeutic target in men with prostate cancer and bone metastases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Modulation of Src activity by low molecular weight protein tyrosine phosphatase during osteoblast differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Successful vitrification of human amnion-derived mesenchymal stem cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Inhibition of protein kinase c-Src as a therapeutic approach for cancer and bone metastases.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Molecular mechanisms and treatment of bone metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

SRC inhibitors in metastatic bone disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Estrogen receptor alpha genotype confers interindividual variability of response to estrogen and testosterone in mesenchymal-stem-cell-derived osteoblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Potent inhibition of platelet-derived growth factor-induced responses in vascular smooth muscle cells by BMS-354825 (dasatinib).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

21 June 2018

Paget disease of bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Bone marrow-derived mesenchymal stem cells already express specific neural proteins before any differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Mesenchymal stem cells: harnessing cell plasticity to tissue and organ repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Src protein-tyrosine kinase structure and regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Adhesion to Vitronectin and Collagen I Promotes Osteogenic Differentiation of Human Mesenchymal Stem Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Oxysterols regulate differentiation of mesenchymal stem cells: pro-bone and anti-fat

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Parathyroid hormone-related peptide interacts with bone morphogenetic protein 2 to increase osteoblastogenesis and decrease adipogenesis in pluripotent C3H10T 1/2 mesenchymal cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Regulation of bone remodeling and emerging breakthrough drugs for osteoporosis and osteolytic bone metastases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Targeting protein kinases for bone disease: discovery and development of Src inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Calcitonin for the long-term prevention and treatment of postmenopausal osteoporosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Decreased c-Src expression enhances osteoblast differentiation and bone formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Advances in the osteoblast lineage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

21 June 2018

Chronic myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Cellular functions regulated by Src family kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Characterization of human bone marrow stromal cells with respect to osteoblastic differentiation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Osteoblasts isolated from mouse calvaria initiate matrix mineralization in culture

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

RANKL expression is related to the differentiation state of human osteoblasts.

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Bone-like nodules formed by human bone marrow stromal cells: comparative study and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

The role of BMP-6, IL-6, and BMP-4 in mesenchymal stem cell-dependent bone development: effects on osteoblastic differentiation induced by parathyroid hormone and vitamin D(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Effects of bisphosphonates on proliferation and osteoblast differentiation of human bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

RETRACTED: Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells

21 January 2018

2 references

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087319

Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

30 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Inhibition of platelet-derived growth factor receptorbeta by imatinib mesylate suppresses proliferation and alters differentiation of human mesenchymal stem cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Platelet-derived growth factor receptor signaling is not involved in osteogenic differentiation of human mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

The Src inhibitor AZD0530 reversibly inhibits the formation and activity of human osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Dasatinib is a potent inhibitor of tumour-associated macrophages, osteoclasts and the FMS receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Therapeutic concentrations of dasatinib inhibit in vitro osteoclastogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Long-term imatinib therapy promotes bone formation in CML patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Increased cortical bone mineralization in imatinib treated patients with chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

21 January 2018

Mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-298

Imatinib Promotes Osteoblast Differentiation by Inhibiting PDGFR Signaling and Inhibits Osteoclastogenesis by Both Direct and Stromal Cell-Dependent Mechanisms

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20565769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Human bone cell cultures in biocompatibility testing. Part I: osteoblastic differentiation of serially passaged human bone marrow cells cultured in α-MEM and in DMEM

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20565769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-10-298

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference