(Q33615294)

English

The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Rong-Jun Guo

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Shinsuke Funakoshi

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Hannah H Lee

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Jianping Kong

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

John P Lynch

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

0 references

publication date

4 September 2009

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

31

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

159-166

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

The homeodomain transcription factor Cdx1 does not behave as an oncogene in normal mouse intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

The homeodomain transcription factors Cdx1 and Cdx2 induce E-cadherin adhesion activity by reducing beta- and p120-catenin tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

The canonical Wnt signalling pathway and its APC partner in colon cancer development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

CDX2 has tumorigenic potential in the human colon cancer cell lines LOVO and SW48.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

The role of Cdx proteins in intestinal development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Cdx1 or Cdx2 expression activates E-cadherin-mediated cell-cell adhesion and compaction in human COLO 205 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Loss of CDX1 expression in colorectal carcinoma: promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Cdx1 inhibits the proliferation of human colon cancer cells by reducing cyclin D1 gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

The genetic pathogenesis of colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Gut-enriched Krüppel-like factor regulates colonic cell growth through APC/beta-catenin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1 alpha to HNF-1 beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

The caudal-related homeodomain protein Cdx1 inhibits proliferation of intestinal epithelial cells by down-regulation of D-type cyclins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Cdx1 promotes differentiation in a rat intestinal epithelial cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

An intestine-specific homeobox gene regulates proliferation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

A homeodomain protein related to caudal regulates intestine-specific gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

28 July 2018

Wnt/beta-catenin signaling in development and disease

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Repression of the desmocollin 2 gene expression in human colon cancer cells is relieved by the homeodomain transcription factors Cdx1 and Cdx2.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Cdk2-dependent phosphorylation of homeobox transcription factor CDX2 regulates its nuclear translocation and proteasome-mediated degradation in human intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP213

21 January 2018

Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

30 October 2018

Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812568

30 October 2018

Regulation of sucrase and lactase in developing rats: role of nuclear factors that bind to two gene regulatory elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional role of Cdx2 in beta-catenin signaling during transdifferentiation in endometrial carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/CARCIN/BGP213

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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