(Q33616462)

28 July 2017

Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons (English)

1 reference

28 July 2017

1 reference

1 reference

1 reference

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21

Rudolf Jaenisch

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Julien Muffat

object named as

Julien Muffat

12

0 references

Michael D. Pluth

object named as

Michael D Pluth

14

0 references

Susan Lindquist

22

object named as

Susan Lindquist

1 reference

28 July 2017

18

Li-Huei Tsai

1 reference

28 July 2017

20

Stephen L Buchwald

1 reference

28 July 2017

Chee Yeun Chung

1

1 reference

28 July 2017

Vikram Khurana

2

1 reference

28 July 2017

Pavan K Auluck

3

1 reference

28 July 2017

Daniel F Tardiff

4

1 reference

28 July 2017

Joseph R Mazzulli

5

1 reference

28 July 2017

Frank Soldner

6

1 reference

28 July 2017

Valeriya Baru

7

1 reference

28 July 2017

Yali Lou

8

1 reference

28 July 2017

Yelena Freyzon

9

1 reference

28 July 2017

Sukhee Cho

10

1 reference

28 July 2017

Alison E Mungenast

11

1 reference

28 July 2017

Maisam Mitalipova

13

1 reference

28 July 2017

Nathan T Jui

15

1 reference

28 July 2017

Birgitt Schüle

16

1 reference

28 July 2017

Stephen J Lippard

17

1 reference

28 July 2017

Dimitri Krainc

19

1 reference

28 July 2017

language of work or name

English

0 references

publication date

24 October 2013

1 reference

28 July 2017

1 reference

28 July 2017

342

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28 July 2017

6161

1 reference

28 July 2017

983-987

1 reference

Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons.

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Nedd4 and Nedd4-2: ubiquitin ligases at work in the neuron.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Neuropathologic substrates of Parkinson disease dementia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Cognitive performance of GBA mutation carriers with early-onset PD: the CORE-PD study.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Visualization of nitric oxide production in the mouse main olfactory bulb by a cell-trappable copper(II) fluorescent probe

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Clinical, neuropathological and genotypic variability in SNCA A53T familial Parkinson's disease. Variability in familial Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Oxygen-regulated isoforms of cytochrome c oxidase have differential effects on its nitric oxide production and on hypoxic signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Fzf1p regulates an inducible response to nitrosative stress in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

alpha-Synuclein locus triplication causes Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Human embryonic stem cell lines derived from discarded embryos

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Clinical and pathological features of a Parkinsonian syndrome in a family with an Ala53Thr alpha-synuclein mutation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Hereditary form of parkinsonism--dementia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Clinical genetic analysis of Parkinson's disease in the Contursi kindred

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022187

Neocortical layer formation of human developing brains and lissencephalies: consideration of layer-specific marker expression.

21 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1245296

Yeast cells provide insight into alpha-synuclein biology and pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1245296

Patterns of protein nitration in dementia with Lewy bodies and striatonigral degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1245296

Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1245296

Autosomal dominant Lewy body parkinsonism in a four-generation family

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1245296

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24158904

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Preparation of a copper-based fluorescent probe for nitric oxide and its use in mammalian cultured cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24158904

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24158904

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1245296

1 reference

28 July 2017

1 reference

28 July 2017

1 reference