(Q33618246)

28 July 2017

Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim. (English)

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28 July 2017

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J Konishi

1

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28 July 2017

F Yi

2

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28 July 2017

X Chen

3

1 reference

28 July 2017

H Vo

4

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28 July 2017

D P Carbone

5

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28 July 2017

T P Dang

6

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28 July 2017

language of work or name

English

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publication date

2 November 2009

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28 July 2017

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28 July 2017

29

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28 July 2017

4

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28 July 2017

589-596

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https://scigraph.springernature.com/pub.10.1038/onc.2009.366

28 July 2017

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cites work

BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Notch3 activation modulates cell growth behaviour and cross-talk to Wnt/TCF signalling pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

The multifaceted role of Notch in cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Involvement of Notch1 in the development of mouse mammary tumors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation.

14 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Development and cancer: lessons learned in the pancreas.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Chromosome 19 translocation, overexpression of Notch3, and human lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Ras pathway signals are required for notch-mediated oncogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Melphalan-induced apoptosis in multiple myeloma cells is associated with a cleavage of Mcl-1 and Bim and a decrease in the Mcl-1/Bim complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.366

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Dimensions Publication ID

28 July 2017

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28 July 2017

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