(Q38333825)

2 September 2017

title

Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2. (English)

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B-cell chronic lymphocytic leukemia

2 September 2017

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Duechler M

1

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2 September 2017

Shehata M

2

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2 September 2017

Schwarzmeier JD

3

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2 September 2017

Hoelbl A

4

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2 September 2017

Hilgarth M

5

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2 September 2017

Hubmann R

6

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2 September 2017

publication date

1 February 2005

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2 September 2017

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2 September 2017

volume

19

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2 September 2017

issue

2

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2 September 2017

page(s)

260-267

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B-cell chronic lymphocytic leukaemia: a polymorphic family unified by genomic features

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Role of apoptosis in the pathogenesis of B-cell chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Notch signaling: cell fate control and signal integration in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Signalling downstream of activated mammalian Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Notch2 haploinsufficiency results in diminished B1 B cells and a severe reduction in marginal zone B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Correlating notch signaling with thymocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Arbiter of differentiation and death: Notch signaling meets apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

The ubiquitin proteolytic system and pathogenesis of human diseases: a novel platform for mechanism-based drug targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Proteasome inhibitors as new anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Ubiquitin-proteasome system and increased sensitivity of B-CLL lymphocytes to apoptotic death activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Proteasome inhibitors in the treatment of B-cell malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Clinical update: proteasome inhibitors in solid tumors

21 January 2018

1 reference

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The proteasome: a novel therapeutic target in haematopoietic malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and function

21 January 2018

1 reference

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Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Deadly encounter: ubiquitin meets apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Activated Notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Toward the rational design of cell fate modifiers: notch signaling as a target for novel biopharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Potential for proteasome inhibition in the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

Chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

7 January 2021

The two CD23 isoforms display differential regulation in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

7 January 2021

Rapid Notch1 nuclear translocation after ligand binding depends on presenilin-associated gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

7 January 2021

Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

7 January 2021

Role and function of the 26S proteasome in proliferation and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

7 January 2021

Peritoneal CD5+ B-1 cells have signaling properties similar to tolerant B cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

7 January 2021

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

7 January 2021

Nuclear NF-ATp is a hallmark of unstimulated B cells from B-CLL patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403592

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403592

1 reference

Dimensions Publication ID

2 September 2017

1043396274

0 references

1 reference