(Q33621245)

English

High-dose lovastatin for acute ischemic stroke: results of the phase I dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART)

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

High-dose lovastatin for acute ischemic stroke: results of the phase I dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART) (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

phase I clinical trial

0 references

1 reference

based on heuristic

inferred from title

2

object named as

Ralph L Sacco

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Mitchell S V Elkind

1

object named as

Mitchell S V Elkind

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Robert B Macarthur

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Ellinor Peerschke

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Greg Neils

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Howard Andrews

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Joshua Stillman

7

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Tania Corporan

8

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Dana Leifer

9

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Rui Liu

10

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Ken Cheung

11

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

publication date

16 July 2009

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Cerebrovascular Diseases

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

28

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

266-275

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Statins as acute-stroke treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

The Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART): an adaptive design phase I dose-escalation study of high-dose lovastatin in acute ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Suppression of stroke-induced progenitor proliferation in adult subventricular zone by tumor necrosis factor receptor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Selecting promising ALS therapies in clinical trials.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Statin use and sex-specific stroke outcomes in patients with vascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Lipid-lowering agent use at ischemic stroke onset is associated with decreased mortality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Current and future aims of lipid-lowering therapy: changing paradigms and lessons from the Heart Protection Study on standards of efficacy and safety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Risk for myopathy with statin therapy in high-risk patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

The statins as anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Statins as anti-inflammatory agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Comparative tolerability of the HMG-CoA reductase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

A phase I-II trial of lovastatin for anaplastic astrocytoma and glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

The continual reassessment method in cancer phase I clinical trials: a simulation study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Continual reassessment method: a practical design for phase 1 clinical trials in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

Estimating the probability of toxicity at the recommended dose following a phase I clinical trial in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

21 June 2018

The medical case for the development of an intravenous statin formulation--beyond ischemic stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Intravenous rosuvastatin for acute stroke treatment: an animal study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Simvastatin in the acute phase of ischemic stroke: a safety and efficacy pilot trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Statin treatment withdrawal in ischemic stroke: a controlled randomized study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

HMG-CoA reductase inhibitors improve acute ischemic stroke outcome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Tumor necrosis factor-alpha receptor 1 is a major predictor of mortality and new-onset heart failure in patients with acute myocardial infarction: the Cytokine-Activation and Long-Term Prognosis in Myocardial Infarction (C-ALPHA) study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Favorable outcome of ischemic stroke in patients pretreated with statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Treatment with statins after induction of focal ischemia in rats reduces the extent of brain damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Withdrawal of statin treatment abrogates stroke protection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Comparative pharmacokinetics of lovastatin extended-release tablets and lovastatin immediate-release tablets in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Simvastatin protects against long-lasting behavioral and morphological consequences of neonatal hypoxic/ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Does pretreatment with statins improve clinical outcome after stroke? A pilot case-referent study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Phase II study of high-dose lovastatin in patients with advanced gastric adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814015

30 October 2018

Effect of pretreatment with statins on the severity of acute ischemic cerebrovascular events

1 reference

https://pubmed.ncbi.nlm.nih.gov/19609078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-dose atorvastatin after stroke or transient ischemic attack

1 reference

https://pubmed.ncbi.nlm.nih.gov/19609078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple technique to evaluate model sensitivity in the continual reassessment method

1 reference

https://pubmed.ncbi.nlm.nih.gov/19609078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential designs for phase I clinical trials with late-onset toxicities

1 reference

https://pubmed.ncbi.nlm.nih.gov/19609078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1159/000228709

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

0 references

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