(Q33622860)

28 July 2017

title

hKSR-2, a vitamin D-regulated gene, inhibits apoptosis in arabinocytosine-treated HL60 leukemia cells (English)

1 reference

28 July 2017

0 references

1 reference

Xuening Wang

1

1 reference

28 July 2017

Rahul Patel

series ordinal

2

1 reference

28 July 2017

George P Studzinski

series ordinal

3

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28 July 2017

publication date

1 September 2008

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Molecular Cancer Therapeutics

28 July 2017

published in

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28 July 2017

volume

7

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28 July 2017

issue

9

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28 July 2017

page(s)

2798-2806

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describes a project that uses

28 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2814415/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Expression of human kinase suppressor of Ras 2 (hKSR-2) gene in HL60 leukemia cells is directly upregulated by 1,25-dihydroxyvitamin D(3) and is required for optimal cell differentiation

14 July 2018

1 reference

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Raf-1 signaling is required for the later stages of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells but is not mediated by the MEK/ERK module

14 July 2018

1 reference

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Induction of kinase suppressor of RAS-1(KSR-1) gene by 1, alpha25-dihydroxyvitamin D3 in human leukemia HL60 cells through a vitamin D response element in the 5'-flanking region

14 July 2018

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14 July 2018

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14 July 2018

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Expression of kinase suppressor of Ras1 enhances cisplatin-induced extracellular signal-regulated kinase activation and cisplatin sensitivity

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Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation

14 July 2018

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Susceptibility to cytosine arabinoside (Ara-C)-induced cytotoxicity in human leukemia cell lines

14 July 2018

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14 July 2018

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14 July 2018

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Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signaling

14 July 2018

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14 July 2018

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Activation of extracellular signal-regulated kinases (ERKs) defines the first phase of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells

14 July 2018

1 reference

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Arsenic trioxide induces apoptosis of myeloid leukemia cells by activation of caspases

14 July 2018

1 reference

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Increased p21/WAF-1 and p53 protein levels following sequential three drug combination regimen of fludarabine, cytarabine and docetaxel induces apoptosis in human leukemia cells.

14 July 2018

1 reference

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KSR stimulates Raf-1 activity in a kinase-independent manner

14 July 2018

1 reference

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14 July 2018

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KSR, a novel protein kinase required for RAS signal transduction

14 July 2018

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14 July 2018

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14 July 2018

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

14 July 2018

1 reference

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Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3

14 July 2018

1 reference

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Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

14 July 2018

1 reference

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All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results

14 July 2018

1 reference

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Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia

14 July 2018

1 reference

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t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism

14 July 2018

1 reference

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Role of kinase suppressor of Ras-1 in neuronal survival signaling by extracellular signal-regulated kinase 1/2.

30 October 2018

1 reference

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Flavopiridol and histone deacetylase inhibitors promote mitochondrial injury and cell death in human leukemia cells that overexpress Bcl-2.

30 October 2018

1 reference

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Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

30 October 2018

1 reference

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The kinase activity of kinase suppressor of Ras1 (KSR1) is independent of bound MEK.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814415

Kinase suppressor of RAS (KSR) amplifies the differentiation signal provided by low concentrations 1,25-dihydroxyvitamin D3.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814415

C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814415

Evidence that activation of MEK1,2/erk1,2 signal transduction pathway is necessary for calcitriol-induced differentiation of HL-60 cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814415

Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814415

Generation of reactive oxygen intermediates after treatment of blasts of acute myeloblastic leukemia with cytosine arabinoside: role of bcl-2.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814415

All-trans retinoic acid and 1 alpha,25-dihydroxyvitamin D3 co-operate to promote differentiation of the human promyeloid leukemia cell line HL60 to monocytes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814415

MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation

30 October 2018

1 reference

12 December 2020

Antiapoptotic action of 1,25-dihydroxyvitamin D3 is associated with increased mitochondrial MCL-1 and RAF-1 proteins and reduced release of cytochrome c

1 reference

12 December 2020

Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells

1 reference

12 December 2020

Mechanism of cytosine arabinoside toxicity to the blast cells of acute myeloblastic leukemia: involvement of free radicals

1 reference

12 December 2020

10.1158/1535-7163.MCT-08-0276

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference