(Q33624748)

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Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and Double JS-K, through incorporation into PEG-protected nanoparticles

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and Double JS-K, through incorporation into PEG-protected nanoparticles (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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Robert Prud'homme

6

object named as

Robert K Prud'homme

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Varun Kumar

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Sam Y Hong

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Anna E Maciag

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Joseph E Saavedra

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Douglas H Adamson

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Larry K Keefer

7

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Harinath Chakrapani

8

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

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publication date

1 February 2010

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Europe PubMed Central

PubMed publication ID

28 July 2017

Molecular Pharmaceutics

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Europe PubMed Central

PubMed publication ID

28 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

291-298

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

The nitric oxide prodrug JS-K and its structural analogues as cancer therapeutic agents

1 reference

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Effects of branching architecture and linker on the activity of hyperbranched polymer-drug conjugates

1 reference

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21 June 2018

Poly(amidoamine) dendrimer-drug conjugates with disulfide linkages for intracellular drug delivery

1 reference

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21 June 2018

Aryl bis(diazeniumdiolates): potent inducers of S-glutathionylation of cellular proteins and their in vitro antiproliferative activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Nitric oxide prodrug JS-K inhibits ubiquitin E1 and kills tumor cells retaining wild-type p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

TIMP-2 mediates the anti-invasive effects of the nitric oxide-releasing prodrug JS-K in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Modulating the therapeutic activity of nanoparticle delivered paclitaxel by manipulating the hydrophobicity of prodrug conjugates.

1 reference

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21 June 2018

Synthesis and in vitro anti-leukemic activity of structural analogues of JS-K, an anti-cancer lead compound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Synthesis, nitric oxide release, and anti-leukemic activity of glutathione-activated nitric oxide prodrugs: Structural analogues of PABA/NO, an anti-cancer lead compound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells

1 reference

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21 June 2018

Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

1 reference

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21 June 2018

A novel role for human sulfiredoxin in the reversal of glutathionylation.

1 reference

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21 June 2018

PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Targeted drug delivery with dendrimers: comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Nitric oxide (NO)- and nitroxyl (HNO)-generating diazeniumdiolates (NONOates): emerging commercial opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Nitric oxide prodrugs and metallochemotherapeutics: JS-K and CB-3-100 enhance arsenic and cisplatin cytolethality by increasing cellular accumulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

21 June 2018

SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

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Mechanical properties of biodegradable polymers and composites proposed for internal fixation of bone

1 reference

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Biodegradable long-circulating polymeric nanospheres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2815019

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A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

1 reference

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Formulation and stability of itraconazole and odanacatib nanoparticles: governing physical parameters

1 reference

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30 October 2018

Preparation of poly(ethylene glycol) protected nanoparticles with variable bioconjugate ligand density

1 reference

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Thermodynamic limits on drug loading in nanoparticle cores

1 reference

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Composite block copolymer stabilized nanoparticles: simultaneous encapsulation of organic actives and inorganic nanostructures

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Ostwald ripening of beta-carotene nanoparticles.

1 reference

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30 October 2018

JS-K, a nitric oxide prodrug, induces cytochrome c release and caspase activation in HL-60 myeloid leukemia cells

1 reference

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Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system

1 reference

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30 October 2018

The effect of the linker on the hydrolysis rate of drug-linked ester bonds

1 reference

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Polymer-drug compatibility: a guide to the development of delivery systems for the anticancer agent, ellipticine

1 reference

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JS-K, a novel non-ionic diazeniumdiolate derivative, inhibits Hep 3B hepatoma cell growth and induces c-Jun phosphorylation via multiple MAP kinase pathways.

1 reference

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The secondary amine/nitric oxide complex ion R(2)N[N(O)NO](-) as nucleophile and leaving group in S9N)Ar reactions

1 reference

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Protected peptide nanoparticles: experiments and brownian dynamics simulations of the energetics of assembly

1 reference

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12 December 2020

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10.1021/MP900245H

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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