(Q33624909)

28422076

28 July 2017

title

ZeGlobalTox: An Innovative Approach to Address Organ Drug Toxicity Using Zebrafish (English)

1 reference

28 July 2017

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Carles Cornet

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Simone Calzolari

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Rafael Miñana-Prieto

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Sylvia Dyballa

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Els van Doornmalen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Helma Rutjes

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Thierry Savy

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Javier Terriente

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

19 April 2017

1 reference

28422076

International Journal of Molecular Sciences

28 July 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

6 June 2020

copyright license

start time

19 April 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's disease in zebrafish

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Toxicology Strategies for Drug Discovery: Present and Future

28 July 2018

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Zebrafish as tools for drug discovery

28 July 2018

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Diabetes: Advances in Diagnosis and Treatment

28 July 2018

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An analysis of the attrition of drug candidates from four major pharmaceutical companies

28 July 2018

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Diastereoisomer-specific effects of hexabromocyclododecanes on hepatic aryl hydrocarbon receptors and cytochrome P450s in zebrafish (Danio rerio).

28 July 2018

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15 years of zebrafish chemical screening

28 July 2018

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Comparability of behavioural assays using zebrafish larvae to assess neurotoxicity.

28 July 2018

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Zebrafish as model organisms for studying drug-induced liver injury

28 July 2018

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Energy metabolism in the liver

28 July 2018

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Development of a convenient in vivo hepatotoxin assay using a transgenic zebrafish line with liver-specific DsRed expression

28 July 2018

1 reference

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In vivo zebrafish assays for analyzing drug toxicity

28 July 2018

1 reference

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Transient overexpression of adh8a increases allyl alcohol toxicity in zebrafish embryos

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Clinical development success rates for investigational drugs

28 July 2018

1 reference

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Exploratory toxicology as an integrated part of drug discovery. Part I: Why and how.

28 July 2018

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Zebrafish models of human liver development and disease

28 July 2018

1 reference

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Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Defining hepatic dysfunction parameters in two models of fatty liver disease in zebrafish larvae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Optimisation of embryonic and larval ECG measurement in zebrafish for quantifying the effect of QT prolonging drugs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Reducing safety-related drug attrition: the use of in vitro pharmacological profiling.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Overlapping cardiac programs in heart development and regeneration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Zebrafish as potential model for developmental neurotoxicity testing: a mini review

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Comparisons between in vitro whole cell imaging and in vivo zebrafish-based approaches for identifying potential human hepatotoxicants earlier in pharmaceutical development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Drinks like a fish: using zebrafish to understand alcoholic liver disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Locomotor behaviors in zebrafish (Danio rerio) larvae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Cardiac arrhythmia:in vivoscreening in the zebrafish to overcome complexity in drug discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Zebrafish as a model for long QT syndrome: the evidence and the means of manipulating zebrafish gene expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Hepatotoxicity of antibacterials: Pathomechanisms and clinical

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

New school in liver development: lessons from zebrafish

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Endogenous dopamine suppresses initiation of swimming in prefeeding zebrafish larvae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Synergistic induction of AHR regulated genes in developmental toxicity from co-exposure to two model PAHs in zebrafish

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Zebrafish: an emerging model system for human disease and drug discovery.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Fatty acid metabolism in adipose tissue, muscle and liver in health and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Can the pharmaceutical industry reduce attrition rates?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Concordance of the toxicity of pharmaceuticals in humans and in animals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in perfused rat liver: involvement of hepatic aldehyde oxidase as a detoxification enzyme

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Fusidic acid adverse drug reactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Suramin, an active drug for prostate cancer: interim observations in a phase I trial

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Digitalis metabolism and human liver alcohol dehydrogenase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Epinephrine-induced insulin resistance in man.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

Lessons from 60 years of pharmaceutical innovation

28 July 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Why drugs fail--a study on side effects in new chemical entities.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Regulatory aspects on the use of fish embryos in environmental toxicology.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

A multi-endpoint in vivo larval zebrafish (Danio rerio) model for the assessment of integrated cardiovascular function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Metabolism of ethanol and associated hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Suramin's development: what did we learn?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Drug-induced liver steatosis and phospholipidosis: cell-based assays for early screening of drug candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

High-throughput assay for small molecules that modulate zebrafish embryonic heart rate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Acute neuroactive drug exposures alter locomotor activity in larval zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Blood glucose level and outcome after cardiac arrest: insights from a large registry in the hypothermia era.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Toward predictive models for drug-induced liver injury in humans: are we there yet?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Locomotion in larval zebrafish: Influence of time of day, lighting and ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18040864

Neurochemical and behavioural changes in zebrafish Danio rerio after systemic administration of 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412445

A zebrafish phenotypic assay for assessing drug-induced hepatotoxicity

30 October 2018

1 reference

12 December 2020

[Finasteride-induced hepatitis]

1 reference

12 December 2020

The effect of acute hyperglycaemia on QTc duration in healthy man

1 reference

12 December 2020

Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS18040864

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422076%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

28422076

1 reference