(Q33632353)

28 July 2017

title

Metformin protects against systolic overload-induced heart failure independent of AMP-activated protein kinase α2. (English)

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28 July 2017

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14

Benoit Viollet

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28 July 2017

Zhongbing Lu

2

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Yingjie Chen

object named as

Yingjie Chen

17

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author name string

Xin Xu

1

1 reference

28 July 2017

John Fassett

3

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28 July 2017

Ping Zhang

4

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28 July 2017

Xinli Hu

5

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28 July 2017

Xiaoyu Liu

6

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28 July 2017

Dongmin Kwak

7

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28 July 2017

Jingxin Li

8

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28 July 2017

Guangshuo Zhu

9

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28 July 2017

Yi Tao

10

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28 July 2017

Mingxiao Hou

11

1 reference

28 July 2017

Huan Wang

12

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28 July 2017

Haipeng Guo

13

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28 July 2017

Edward O McFalls

15

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28 July 2017

Robert J Bache

16

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28 July 2017

language of work or name

English

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publication date

13 January 2014

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28 July 2017

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28 July 2017

volume

63

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28 July 2017

issue

4

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28 July 2017

page(s)

723-728

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Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

AMPK attenuates microtubule proliferation in cardiac hypertrophy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

AMPKα2 deletion exacerbates neointima formation by upregulating Skp2 in vascular smooth muscle cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

AMP activated protein kinase-α2 regulates expression of estrogen-related receptor-α, a metabolic transcription factor related to heart failure development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Adenosine kinase regulation of cardiomyocyte hypertrophy.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure-overloaded left ventricle

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Ecto-5'-nucleotidase deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: systematic review

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Thiazolidinediones, metformin, and outcomes in older patients with diabetes and heart failure: an observational study

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin and thiazolidinedione use in Medicare patients with heart failure

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026291

Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24420540

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1161/HYPERTENSIONAHA.113.02619

1 reference

28 July 2017

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28 July 2017

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