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B cell development: signal transduction by antigen receptors and their surrogates.
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Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
review article
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Europe PubMed Central
title
B cell development: signal transduction by antigen receptors and their surrogates
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author
John Cambier
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author name string
R J Benschop
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
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7 December 2019
publication date
1 April 1999
1 reference
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Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
volume
11
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
page(s)
143-151
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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The Ig alpha/Igbeta heterodimer on mu-negative proB cells is competent for transducing signals to induce early B cell differentiation
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A critical role of λ5 protein in B cell development
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7 January 2021
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Precursor B cells showing H chain allelic inclusion display allelic exclusion at the level of pre-B cell receptor surface expression
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7 January 2021
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Transitional B cells are the target of negative selection in the B cell compartment
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7 January 2021
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RAG-1-deficient mice have no mature B and T lymphocytes
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7 January 2021
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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
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A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
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7 January 2021
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Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development
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7 January 2021
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Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals
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7 January 2021
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Receptor editing in self-reactive bone marrow B cells
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7 January 2021
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Receptor editing occurs frequently during normal B cell development.
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7 January 2021
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Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection.
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7 January 2021
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Autoreactive B cell regulation: peripheral induction of developmental arrest by lupus-associated autoantigens.
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7 January 2021
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Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B-cell tolerance
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7 January 2021
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In vitro tolerance induction of neonatal murine B cells
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7 January 2021
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Antigen receptor signaling: integration of protein tyrosine kinase functions.
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7 January 2021
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The complexity of signaling pathways activated by the BCR.
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7 January 2021
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BLNK: a central linker protein in B cell activation
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7 January 2021
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SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation
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7 January 2021
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T cell activation by clustered tyrosine kinases
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7 January 2021
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inferred from DOI database lookup
Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization
1 reference
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7 January 2021
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Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation
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7 January 2021
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SHIP modulates immune receptor responses by regulating membrane association of Btk.
1 reference
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Crossref
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7 January 2021
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Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.
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7 January 2021
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Different protein tyrosine kinases are required for B cell antigen receptor-mediated activation of extracellular signal-regulated kinase, c-Jun NH2-terminal kinase 1, and p38 mitogen-activated protein kinase.
1 reference
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7 January 2021
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Involvement of guanosine triphosphatases and phospholipase C-gamma2 in extracellular signal-regulated kinase, c-Jun NH2-terminal kinase, and p38 mitogen-activated protein kinase activation by the B cell antigen receptor.
1 reference
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Crossref
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Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.
1 reference
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Crossref
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7 January 2021
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Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice
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Crossref
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7 January 2021
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Normal lymphocyte development but delayed humoral immune response in CD81-null mice
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD22 regulates thymus-independent responses and the lifespan of B cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD22 is a negative regulator of B-cell receptor signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hyperresponsive B cells in CD22-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B lymphocyte antigen receptors (mIg) are non-covalently associated with a disulfide linked, inducibly phosphorylated glycoprotein complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Manipulation of B cell antigen receptor tyrosine phosphorylation using aluminum fluoride and sodium orthovanadate.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of Ig beta in precursor B cell transition and allelic exclusion
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syk tyrosine kinase required for mouse viability and B-cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of p59fynT in interleukin-5 receptor signaling
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Surface IgM-stimulated proliferation, inositol phospholipid hydrolysis, Ca2+ flux, and tyrosine phosphorylation are not altered in B cells from p59fyn-1- mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the B cell by CD22: a requirement for Lyn
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of B cell development by Ras-mediated activation of Raf.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abrogation of autoimmune disease in Lyn-deficient mice by the mutation of the Btk gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hematopoietic cell phosphatase, SHP-1, is constitutively associated with the SH2 domain-containing leukocyte protein, SLP-76, in B cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential activation of transcription factors induced by Ca2+ response amplitude and duration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Murine B lymphopoiesis: towards a unified model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immunoglobulin (Ig)alpha and Igbeta cytoplasmic domains are independently sufficient to signal B cell maturation and activation in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980025-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(99)80025-9
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
PubMed ID
10322153
1 reference
stated in
Europe PubMed Central
PubMed ID
10322153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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