(Q33634337)

English

Substitution of serine for proline in the active center of type 2 iodothyronine deiodinase substantially alters its in vitro biochemical properties with dithiothreitol but not its function in intact cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Substitution of serine for proline in the active center of type 2 iodothyronine deiodinase substantially alters its in vitro biochemical properties with dithiothreitol but not its function in intact cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

3

object named as

John W Harney

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

6

object named as

P Reed Larsen

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Iuri Martin Goemann

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Balázs Gereben

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Bo Zhu

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Ana Luiza Maia

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

0 references

publication date

4 December 2009

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

151

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

821-829

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Cellular and structural biology of the deiodinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Substitution of Cysteine for Selenocysteine in the Catalytic Center of Type III Iodothyronine Deiodinase Reduces Catalytic Efficiency and Alters Substrate Preference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

The role of selenocysteine 133 in catalysis by the human type 2 iodothyronine deiodinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Selective proteolysis of human type 2 deiodinase: a novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Isolation of human type 2 deiodinase gene promoter and characterization of a functional cyclic adenosine monophosphate response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Type 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Characterization of a propylthiouracil-insensitive type I iodothyronine deiodinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Molecular biological and biochemical characterization of the human type 2 selenodeiodinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Substrate requirement for inactivation of iodothyronine-5'-deiodinase activity by thiouracil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Kinetic characteristics of a thioredoxin-activated rat hepatic and renal low-Km iodothyronine 5'-deiodinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Type I iodothyronine deiodinase is a selenocysteine-containing enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

The cDNA for the type I iodothyronine 5‘-deiodinase encodes an enzyme manifesting both high Km and low Km activity. Evidence that rat liver and kidney contain a single enzyme which converts thyroxine to 3,5,3‘-triiodothyronine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Observations on the factors that control the generation of triiodothyronine from thyroxine in rat liver and the nature of the defect induced by fasting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Subcellular localization of a rat liver enzyme converting thyroxine into tri-iodothyronine and possible involvement of essential thiol groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

21 June 2018

Conserved cysteines in the type 1 deiodinase selenoprotein are not essential for catalytic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

30 October 2018

Regulation of iodothyronine 5'-deiodinases: effects of thiol blockers and altered substrate levels in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817617

30 October 2018

The Effects and Interactions of Substrates, Inhibitors, and the Cellular Thiol- Disulfide Balance on the Regulation of Type II Iodothyronine 5′-Deiodinase*

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of glutathione on iodothyronine 5'-deiodinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation and assay of mammalian thioredoxin and thioredoxin reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyroxine 5'-deiodinase activity of rat kidney: observations on activation by thiols and inhibition by propylthiouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of iodothyronine-5′-deiodinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iodothyronine 5'-deiodinase from rat kidney: substrate specificity and the 5'-deiodination of reverse triiodothyronine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin stimulates enzymatic outer ring monodeiodination of reverse triiodothronine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2009-0980

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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