(Q33635227)

28 July 2017

beta-Strand interactions at the domain interface critical for the stability of human lens gammaD-crystallin (English)

1 reference

28 July 2017

Payel Das

1

1 reference

PubMed ID

19937657

28 July 2017

Jonathan A King

series ordinal

2

1 reference

PubMed ID

19937657

28 July 2017

Ruhong Zhou

series ordinal

3

1 reference

28 July 2017

1 January 2010

1 reference

28 July 2017

1 reference

28 July 2017

19

1 reference

28 July 2017

1

1 reference

28 July 2017

131-140

1 reference

Hydrophobic core mutations associated with cataract development in mice destabilize human gammaD-crystallin

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Mechanism of the very efficient quenching of tryptophan fluorescence in human gamma D- and gamma S-crystallins: the gamma-crystallin fold may have evolved to protect tryptophan residues from ultraviolet photodamage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Mechanism of the efficient tryptophan fluorescence quenching in human gammaD-crystallin studied by time-resolved fluorescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Computational protein design: structure, function and combinatorial diversity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Destruction of long-range interactions by a single mutation in lysozyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Identification of a collapsed intermediate with non-native long-range interactions on the folding pathway of a pair of Fyn SH3 domain mutants by NMR relaxation dispersion spectroscopy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Protein folding-simulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Early events in protein folding explored by rapid mixing methods

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Beta-sheet folding mechanisms from perturbation energetics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Contributions of hydrophobic domain interface interactions to the folding and stability of human gammaD-crystallin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Global data on visual impairment in the year 2002

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Posterior capsule opacification: a review of the aetiopathogenesis, experimental and clinical studies and factors for prevention

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

The effects of nonnative interactions on protein folding rates: theory and simulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Dramatic acceleration of protein folding by stabilization of a nonnative backbone conformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Recent advances in the development and application of implicit solvent models in biomolecule simulations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Formation of the folding nucleus of an SH3 domain investigated by loosely coupled molecular dynamics simulations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Crystallin genes: specialization by changes in gene regulation may precede gene duplication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Molecular dynamics simulation of the SH3 domain aggregation suggests a generic amyloidogenesis mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Absolute comparison of simulated and experimental protein-folding dynamics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Can a continuum solvent model reproduce the free energy landscape of a beta -hairpin folding in water?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

All-Atom Structure Prediction and Folding Simulations of a Stable Protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Non-native interactions, effective contact order, and protein folding: a mutational investigation with the energetically frustrated hydrophobic model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Molecular dynamics simulations of biomolecules

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Molecular dynamics simulations of biological reactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Unspecific hydrophobic stabilization of folding transition states

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Lens proteomics: analysis of rat crystallin sequences and two-dimensional electrophoresis map

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

The free energy landscape for beta hairpin folding in explicit water

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Crystal cataracts: human genetic cataract caused by protein crystallization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Folding simulations of a three-stranded antiparallel beta -sheet peptide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Kinetics, thermodynamics and evolution of non-native interactions in a protein folding nucleus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Mechanisms and kinetics of beta-hairpin formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

De novo design of a monomeric three-stranded antiparallel beta-sheet

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

The folding kinetics and thermodynamics of the Fyn-SH3 domain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Folding dynamics of the src SH3 domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Folding dynamics and mechanism of beta-hairpin formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Cataract as a protein condensation disease: the Proctor Lecture.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Mutational analysis of hydrophobic domain interactions in gamma B-crystallin from bovine eye lens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Role of a nonnative interaction in the folding of the protein G B1 domain as inferred from the conformational analysis of the alpha-helix fragment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Navigating the folding routes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Principles of protein folding--a perspective from simple exact models.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Thermodynamic and kinetic analysis of the SH3 domain of spectrin shows a two-state folding transition.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

A salt bridge stabilizes the helix formed by isolated C-peptide of RNase A

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

The evolution of lenticular proteins: the beta- and gamma-crystallin super gene family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Helix signals in proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Crystallin gene expression during rat lens development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Site of carbamoylation of bovine gamma-II-crystallin by potassium [14C]cyanate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Developmental roles and clinical significance of hedgehog signaling

21 June 2018

1 reference

Hedgehog signaling in development and cancer.

21 January 2018

1 reference

Hedgehog: functions and mechanisms

21 January 2018

1 reference

Wnt/beta-catenin signaling: components, mechanisms, and diseases

21 January 2018

1 reference

Hedgehog signalling in cancer formation and maintenance

21 January 2018

1 reference

Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis.

21 January 2018

1 reference

The Hedgehog protein family

21 January 2018

1 reference

Evolution of hedgehog and hedgehog-related genes, their origin from Hog proteins in ancestral eukaryotes and discovery of a novel Hint motif

21 January 2018

1 reference

The hedgehog signaling pathway: where did it come from?

21 January 2018

1 reference

The Pfam protein families database

21 January 2018

1 reference

Characterization of the physical interaction of Gli proteins with SUFU proteins

21 January 2018

1 reference

Suppressor of fused regulates Gli activity through a dual binding mechanism

21 January 2018

1 reference

FFAS03: a server for profile--profile sequence alignments

21 January 2018

1 reference

Solvent content of protein crystals

21 January 2018

1 reference

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

21 January 2018

1 reference

Searching protein structure databases with DaliLite v.3

21 January 2018

1 reference

Flexible structure alignment by chaining aligned fragment pairs allowing twists

21 January 2018

1 reference

Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

21 January 2018

1 reference

Multiple sequence alignment using ClustalW and ClustalX

21 January 2018

1 reference

ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

21 January 2018

1 reference

STRING 8--a global view on proteins and their functional interactions in 630 organisms

21 January 2018

1 reference

Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491

21 January 2018

1 reference

Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.

21 January 2018

1 reference

TOPSAN: use of a collaborative environment for annotating, analyzing and disseminating data on JCSG and PSI structures

21 January 2018

1 reference

TOPSAN: a collaborative annotation environment for structural genomics

21 January 2018

1 reference

Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts

21 January 2018

1 reference

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

21 January 2018

1 reference

Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline

21 January 2018

1 reference

An automated system to mount cryo-cooled protein crystals on a synchrotron beam line, using compact sample cassettes and a small-scale robot

21 January 2018

1 reference

Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines

21 January 2018

1 reference

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

1 reference

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

21 January 2018

A short history of SHELX

1 reference

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

21 January 2018

1 reference

Features and development of Coot

21 January 2018

1 reference

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

Automated and accurate deposition of structures solved by X-ray diffraction to the Protein Data Bank

21 January 2018

1 reference

WHAT IF: a molecular modeling and drug design program

21 January 2018

1 reference

SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model

21 January 2018

1 reference

Maximum-likelihood density modification

21 January 2018

1 reference

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

Validation of protein crystal structures

21 January 2018

1 reference

Inference of macromolecular assemblies from crystalline state

21 January 2018

1 reference

PDBsum more: new summaries and analyses of the known 3D structures of proteins and nucleic acids

21 January 2018

1 reference

PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations

21 January 2018

1 reference

Electrostatics of nanosystems: application to microtubules and the ribosome

21 January 2018

1 reference

Folding and stability of the isolated Greek key domains of the long-lived human lens proteins gammaD-crystallin and gammaS-crystallin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

The effect of increasing the stability of non-native interactions on the folding landscape of the bacterial immunity protein Im9.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Urochordate betagamma-crystallin and the evolutionary origin of the vertebrate eye lens.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Interdomain side-chain interactions in human gammaD crystallin influencing folding and stability

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Probing folding and fluorescence quenching in human gammaD crystallin Greek key domains using triple tryptophan mutant proteins

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Free energy surfaces of beta-hairpin and alpha-helical peptides generated by replica exchange molecular dynamics with the AGBNP implicit solvent model

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

In vitro unfolding, refolding, and polymerization of human gammaD crystallin, a protein involved in cataract formation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Long-range interactions within a nonnative protein

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

A collapsed intermediate with nonnative packing of hydrophobic residues in the folding of TEM-1 beta-lactamase.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Guanidinium chloride induction of partial unfolding in amide proton exchange in RNase A.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Aggregation of beta A3-crystallin is independent of the specific sequence of the domain connecting peptide.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

An approach to rapid protein crystallization using nanodroplets

30 October 2018

1 reference

Mapping the Conformational Landscape of Urea-Denatured Ubiquitin Using Residual Dipolar Couplings

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Direct Observation of Dipolar Couplings and Hydrogen Bonds across a β-Hairpin in 8 M Urea

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Mutation Causing Self-Aggregation in Human γC-Crystallin Leading to Congenital Cataract

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817848

Domain interactions and connecting peptides in lens crystallins

30 October 2018

1 reference

12 December 2020

Beta-hairpin folding simulations in atomistic detail using an implicit solvent model

1 reference

12 December 2020

X-ray analysis of the eye lens protein gamma-II crystallin at 1.9 A resolution

1 reference

12 December 2020

Crystal structure of calf eye lens gamma-crystallin IIIb at 2.5 A resolution: its relation to function

1 reference

12 December 2020

Glutamine deamidation destabilizes human gammaD-crystallin and lowers the kinetic barrier to unfolding

1 reference

12 December 2020

Identifiers

DOI

10.1002/PRO.497

1 reference

28 July 2017

1 reference

28 July 2017

1 reference

PubMed ID

19937657