(Q33644326)

28 July 2017

title

PTK6 regulates IGF-1-induced anchorage-independent survival (English)

1 reference

28 July 2017

PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival (English)

1 reference

10.1371/JOURNAL.PONE.0011729

DOI

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0011729

12 June 2024

15

William C Hahn

1 reference

28 July 2017

13

Kornelia Polyak

1 reference

28 July 2017

14

Gordon B Mills

1 reference

28 July 2017

16

Joan S Brugge

1 reference

28 July 2017

3

Laura M. Selfors

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

12 June 2024

10

Charles B. Epstein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

12 June 2024

author name string

Yashaswi Shrestha

2

1 reference

28 July 2017

Fabianne Frye

4

1 reference

28 July 2017

Naoko Iida

5

1 reference

28 July 2017

Zhigang Wang

6

1 reference

28 July 2017

Lihua Zou

7

1 reference

28 July 2017

Jun Yao

8

1 reference

28 July 2017

Yiling Lu

9

1 reference

28 July 2017

Sridaran Natesan

11

1 reference

28 July 2017

Hanna Y. Irie

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

12 June 2024

Andrea L. Richardson

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

12 June 2024

Joan S. Brugge

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

12 June 2024

language of work or name

English

0 references

publication date

23 July 2010

1 reference

full work available at URL

28 July 2017

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011729&type=printable

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20668531/pdf/?tool=EBI

12 June 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20668531/?tool=EBI

12 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

https://europepmc.org/articles/PMC2909213

12 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

https://europepmc.org/articles/PMC2909213?pdf=render

12 June 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20668531

http://dx.plos.org/10.1371/journal.pone.0011729

12 June 2024

1 reference

10.1371/JOURNAL.PONE.0011729

DOI

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0011729

12 June 2024

1 reference

28 July 2017

volume

5

1 reference

28 July 2017

issue

7

1 reference

28 July 2017

page(s)

e11729

1 reference

Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

23 July 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2909213/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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21 June 2018

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Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Induction of protein tyrosine kinase 6 in mouse intestinal crypt epithelial cells promotes DNA damage-induced apoptosis

21 June 2018

1 reference

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Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells

21 June 2018

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Oncogenic functions of PTK6 are enhanced by its targeting to plasma membrane but abolished by its targeting to nucleus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation

21 June 2018

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Igf1r as a therapeutic target in a mouse model of basal-like breast cancer

21 June 2018

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The paradox of autophagy and its implication in cancer etiology and therapy

21 June 2018

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BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells

21 June 2018

1 reference

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Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.

21 June 2018

1 reference

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Genome-wide functional synergy between amplified and mutated genes in human breast cancer

21 June 2018

1 reference

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Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Brk is coamplified with ErbB2 to promote proliferation in breast cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Anoikis: a necessary death program for anchorage-dependent cells

21 June 2018

1 reference

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Anoikis resistance and tumor metastasis

21 June 2018

1 reference

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Induction of autophagy during extracellular matrix detachment promotes cell survival

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Integrative genomic approaches identify IKBKE as a breast cancer oncogene

21 June 2018

1 reference

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Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas.

21 June 2018

1 reference

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

21 June 2018

1 reference

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Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

The BRK tyrosine kinase is expressed in high-grade serous carcinoma of the ovary

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

The molecular portraits of breast tumors are conserved across microarray platforms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Interaction between Brk kinase and insulin receptor substrate-4.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

BRCA1 promoter methylation in sporadic breast tumors: relationship to gene expression profiles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Repeated observation of breast tumor subtypes in independent gene expression data sets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Gene expression profiling predicts clinical outcome of breast cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

The IGF-I receptor in cancer research

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

Prevalence of amplification of the oncogenes c-myc, HER2/neu, and int-2 in one thousand human breast tumours: correlation with steroid receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909213

The insulin-like growth factor I receptor gene is the target for the 15q26 amplicon in breast cancer.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0011729

The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0011729

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0011729

Life and death partners: apoptosis, autophagy and the cross-talk between them

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0011729

Overexpression of PTK6 (breast tumor kinase) protein--a prognostic factor for long-term breast cancer survival--is not due to gene amplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0011729

BRK tyrosine kinase expression in a high proportion of human breast carcinomas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20668531

12 December 2020

inferred from PubMed ID database lookup

IGF-I in epithelial ovarian cancer and its role in disease progression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20668531

12 December 2020

inferred from PubMed ID database lookup

Predicting features of breast cancer with gene expression patterns

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20668531

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0011729

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference