(Q33646781)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

The MafA transcription factor becomes essential to islet β-cells soon after birth (English)

1 reference

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7 March 2020

3

1 reference

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7 March 2020

William S Bush

6

1 reference

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7 March 2020

author name string

Yan Hang

1

1 reference

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7 March 2020

Tsunehiko Yamamoto

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Marcela Brissova

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Min Guo

5

1 reference

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7 March 2020

David W Piston

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Alvin C Powers

8

1 reference

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7 March 2020

Mark Magnuson

9

1 reference

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7 March 2020

Debbie C Thurmond

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Roland Stein

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

language of work or name

English

0 references

publication date

11 February 2014

1 reference

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7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

issue

6

1 reference

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7 March 2020

page(s)

1994-2005

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

7 March 2020

copyright license

start time

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

The role of aging upon β cell turnover

1 reference

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GATA4 and GATA6 control mouse pancreas organogenesis.

21 June 2018

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Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

21 June 2018

1 reference

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Monogenic models: what have the single gene disorders taught us?

21 June 2018

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Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms

21 June 2018

1 reference

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The lessons of early-onset monogenic diabetes for the understanding of diabetes pathogenesis

21 June 2018

1 reference

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Self-renewing endodermal progenitor lines generated from human pluripotent stem cells

21 June 2018

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Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Loss of granuphilin and loss of syntaxin-1A cause differential effects on insulin granule docking and fusion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

MafA and MafB activity in pancreatic β cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Pancreas organogenesis: from bud to plexus to gland

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Phosphorylation within the MafA N terminus regulates C-terminal dimerization and DNA binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

21 June 2018

1 reference

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On the origin of the beta cell

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

MafA is a dedicated activator of the insulin gene in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

21 June 2018

1 reference

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pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

21 June 2018

1 reference

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Signal transducer and activator of transcription 3-regulated sarcoendoplasmic reticulum Ca2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

MafB is required for islet beta cell maturation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

21 June 2018

1 reference

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In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Critical role of gap junction coupled KATP channel activity for regulated insulin secretion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

MafA is a key regulator of glucose-stimulated insulin secretion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Opposing actions of Arx and Pax4 in endocrine pancreas development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Signaling and transcriptional control of pancreatic organogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4030115

30 October 2018

Identifiers

DOI

10.2337/DB13-1001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

24520122

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24520122%20AND%20SRC:MED&resulttype=core&format=json