(Q33662075)

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Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.

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13 February 2020

Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response (English)

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13 February 2020

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insulin resistance

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Robert S Chapkin

13

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13 February 2020

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Yuqing Huo

1

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13 February 2020

Xin Guo

2

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13 February 2020

Honggui Li

3

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13 February 2020

Huan Wang

4

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13 February 2020

Weiyu Zhang

5

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13 February 2020

Ying Wang

6

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13 February 2020

Huaijun Zhou

7

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13 February 2020

Zhanguo Gao

8

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13 February 2020

Sucheta Telang

9

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13 February 2020

Jason Chesney

10

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13 February 2020

Y Eugene Chen

11

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13 February 2020

Jianping Ye

12

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13 February 2020

Chaodong Wu

14

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13 February 2020

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30 November 2009

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13 February 2020

Journal of Biological Chemistry

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13 February 2020

285

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13 February 2020

6

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13 February 2020

3713-3721

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13 February 2020

Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis

1 reference

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Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue.

1 reference

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Characterization of a newly developed chicken 44K Agilent microarray

1 reference

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Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone

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Mechanisms of obesity-associated insulin resistance: many choices on the menu

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21 June 2018

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

1 reference

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21 June 2018

The adipocyte as an active participant in energy balance and metabolism

1 reference

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Adipocytes as regulators of energy balance and glucose homeostasis

1 reference

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21 June 2018

Transcriptional control of adipocyte formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823512

21 June 2018

Expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase/PFKFB3 isoforms in adipocytes and their potential role in glycolytic regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823512

21 June 2018

Regulation of the regulatory enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823512

21 June 2018

Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823512

21 June 2018

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

1 reference

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PPARs and the complex journey to obesity

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21 June 2018

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823512

21 June 2018

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823512

21 June 2018

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity

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1 reference

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Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle

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A central role for JNK in obesity and insulin resistance

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Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

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Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

1 reference

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1 reference

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1 reference

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21 June 2018

Overexpression of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production

1 reference

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Obesity and insulin resistance

1 reference

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Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)

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High-fat diet induced adiposity and insulin resistance in mice lacking the myotonic dystrophy protein kinase.

1 reference

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1 reference

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1 reference

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Elevated total and central adiposity and low physical activity are associated with insulin resistance in children.

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1 reference

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Rosiglitazone improves muscle insulin sensitivity, irrespective of increased triglyceride content, in ob/ob mice

1 reference

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Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

1 reference

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FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis

1 reference

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Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance

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Targeted disruption of inducible 6-phosphofructo-2-kinase results in embryonic lethality.

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1 reference

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12 December 2020

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Perturbation of glucose flux in the liver by decreasing F26P2 levels causes hepatic insulin resistance and hyperglycemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19948719

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based on heuristic

inferred from PubMed ID database lookup

Remodeling of white adipose tissue after retinoic acid administration in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19948719

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inferred from PubMed ID database lookup

The interplay between nutrients and the adipose tissue

1 reference

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inferred from PubMed ID database lookup

Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19948719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C57BL/6J and A/J mice fed a high-fat diet delineate components of metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19948719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High fat diets elevate adipose tissue-derived tumor necrosis factor-alpha activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19948719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.058446

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19948719%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19948719%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19948719%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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