(Q33662919)

English

ALDH+ tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ-secretase inhibitor and irinotecan in colorectal cancer

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ALDH+ tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ-secretase inhibitor and irinotecan in colorectal cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

colorectal cancer

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

Marileila Varella-Garcia

3

object named as

Marileila Varella-Garcia

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

7

object named as

Todd M Pitts

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Wells A Messersmith

12

object named as

Wells A Messersmith

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

John J Arcaroli

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Rebecca W Powell

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Martine McManus

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Aik Choon Tan

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Kevin S Quackenbush

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Dexiang Gao

8

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Anna Spreafico

9

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Arvind Dasari

10

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Basel M Touban

11

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

publication date

28 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Molecular Oncology

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

370-381

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Notch1 regulates the growth of human colon cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Targeting Notch to target cancer stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Cancer statistics, 2009

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Notch1 expression in colorectal carcinoma determines tumor differentiation status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Identification of cells initiating human melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

KEGG for linking genomes to life and the environment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Identification of pancreatic cancer stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Establishment of human colon cancer cell lines from fresh tumors versus xenografts: comparison of success rate and cell line features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Identification and expansion of human colon-cancer-initiating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

The Notch pathway in ovarian carcinomas and adenomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Identification of human brain tumour initiating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Notch1 and notch2 have opposite effects on embryonal brain tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

21 June 2018

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4033713

30 October 2018

High level of Notch1 protein is associated with poor overall survival in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An in vivo platform for translational drug development in pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22521243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLONC.2012.03.004

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33662919&oldid=1738909078"