(Q33676546)

28 July 2017

title

A fundamental trade-off in covalent switching and its circumvention by enzyme bifunctionality in glucose homeostasis (English)

1 reference

28 July 2017

7

1 reference

28 July 2017

Jason W Locasale

5

0 references

Uri Alon

6

object named as

Uri Alon

1 reference

28 July 2017

Tathagata Dasgupta

1

1 reference

28 July 2017

David H Croll

2

1 reference

28 July 2017

Jeremy A Owen

3

1 reference

28 July 2017

Matthew G Vander Heiden

4

1 reference

28 July 2017

Jeremy Gunawardena

8

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28 July 2017

language of work or name

English

0 references

publication date

14 March 2014

1 reference

Journal of Biological Chemistry

28 July 2017

published in

1 reference

28 July 2017

volume

289

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28 July 2017

issue

19

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28 July 2017

page(s)

13010-13025

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Sensitivity and robustness in covalent modification cycles with a bifunctional converter enzyme

28 July 2017

cites work

1 reference

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Time-scale separation--Michaelis and Menten's old idea, still bearing fruit

21 June 2018

1 reference

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The utility of paradoxical components in biological circuits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Dimerization and bifunctionality confer robustness to the isocitrate dehydrogenase regulatory system in Escherichia coli

21 June 2018

1 reference

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Realistic enzymology for post-translational modification: zero-order ultrasensitivity revisited

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

A linear framework for time-scale separation in nonlinear biochemical systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Control of glycolysis through regulation of PFK1: old friends and recent additions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Robust control of PEP formation rate in the carbon fixation pathway of C(4) plants by a bi-functional enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Molecular determinants of liver zonation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

The scaffold protein Ste5 directly controls a switch-like mating decision in yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Structural sources of robustness in biochemical reaction networks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

The rational parameterization theorem for multisite post-translational modification systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

The regulation of protein phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Unlimited multistability in multisite phosphorylation systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Robustness in glyoxylate bypass regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

The geometry of multisite phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Variability and robustness in T cell activation from regulated heterogeneity in protein levels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Programming with models: modularity and abstraction provide powerful capabilities for systems biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Operating regimes of signaling cycles: statics, dynamics, and noise filtering

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Input output robustness in simple bacterial signaling systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Enzyme localization can drastically affect signal amplification in signal transduction pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Molecular coordination of hepatic glucose metabolism by the 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase:glucokinase complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Modeling networks of coupled enzymatic reactions using the total quasi-steady state approximation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Evolutionary analysis of fructose 2,6-bisphosphate metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Threshold responses to morphogen gradients by zero-order ultrasensitivity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Regulation of the regulatory enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Thermodynamic and kinetic analysis of sensitivity amplification in biological signal transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Critical switch of the metabolic fluxes by phosphofructo-2-kinase:fructose-2,6-bisphosphatase. A kinetic model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Product dependence and bifunctionality compromise the ultrasensitivity of signal transduction cascades

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: suiting structure to need, in a family of tissue-specific enzymes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Fluctuations and quality of control in biological cells: zero-order ultrasensitivity reinvestigated

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

N- and C-termini modulate the effects of pH and phosphorylation on hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a metabolic signaling enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

An amplified sensitivity arising from covalent modification in biological systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Protein phosphorylation as a regulatory device

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Hepatocyte Heterogeneity in the Metabolism of Carbohydrates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036316

Effects of sequestration on signal transduction cascades.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.546515

Laplacian dynamics on general graphs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.546515

Complex-linear invariants of biochemical networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.546515

Robust control of nitrogen assimilation by a bifunctional enzyme in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.546515

Phosphorylation of isocitrate dehydrogenase as a demonstration of enhanced sensitivity in covalent regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.546515

Characterization of the exchange reactions of rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24634222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M113.546515

1 reference

28 July 2017

1 reference

28 July 2017

1 reference