(Q33680759)

28 July 2017

title

MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice (English)

1 reference

intraepithelial neoplasia

28 July 2017

main subject

1 reference

Meredith A Collins

1

1 reference

28 July 2017

Wei Yan

series ordinal

2

1 reference

28 July 2017

Judith S Sebolt-Leopold

series ordinal

3

1 reference

28 July 2017

Marina Pasca di Magliano

series ordinal

4

1 reference

28 July 2017

language of work or name

English

0 references

publication date

6 December 2013

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28 July 2017

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28 July 2017

volume

146

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28 July 2017

issue

3

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28 July 2017

page(s)

822-834.e7

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Canonical wnt signaling is required for pancreatic carcinogenesis

28 July 2017

cites work

1 reference

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Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation

21 June 2018

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Role of immune cells and immune-based therapies in pancreatitis and pancreatic ductal adenocarcinoma

21 June 2018

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Control of cell identity in pancreas development and regeneration

21 June 2018

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Metastatic pancreatic cancer is dependent on oncogenic Kras in mice

21 June 2018

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Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma

21 June 2018

1 reference

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21 June 2018

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Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.

21 June 2018

1 reference

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A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.

21 June 2018

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Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

21 June 2018

1 reference

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Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells

21 June 2018

1 reference

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c-Jun/AP-1 is required for CCK-induced pancreatic acinar cell dedifferentiation and DNA synthesis in vitro.

21 June 2018

1 reference

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Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy

21 June 2018

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Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

21 June 2018

1 reference

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Compartmentalization of pancreatic secretory zymogen granules as revealed by low-voltage transmission electron microscopy

21 June 2018

1 reference

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Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model

21 June 2018

1 reference

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KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.

21 June 2018

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K-RAS mutation in the screening, prognosis and treatment of cancer

21 June 2018

1 reference

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Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice

21 June 2018

1 reference

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Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia

21 June 2018

1 reference

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Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

21 June 2018

1 reference

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 June 2018

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New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8.

21 June 2018

1 reference

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Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

MAP kinase signalling pathways in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

SOX9 is required for maintenance of the pancreatic progenitor cell pool

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Development of farnesyl transferase inhibitors: a review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Notch signaling controls multiple steps of pancreatic differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Effects of mitogen-activated protein kinase signaling pathway inhibition on the development of cerulein-induced acute pancreatitis in mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Targeting RAS and PI3K in lung cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037403

Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini

30 October 2018

1 reference

12 December 2020

Molecular analysis to detect pancreatic ductal adenocarcinoma in high-risk groups

1 reference

12 December 2020

Quantitative immunocytochemical localization of pancreatic secretory proteins in subcellular compartments of the rat acinar cell

1 reference

12 December 2020

Gata6 is required for complete acinar differentiation and maintenance of the exocrine pancreas in adult mice

1 reference

12 December 2020

10.1053/J.GASTRO.2013.11.052

Identifiers

DOI

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28 July 2017

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28 July 2017

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