(Q54783170)

3 June 2018

title

Targeting RAS and PI3K in lung cancer. (English)

1 reference

3 June 2018

author

Julian Downward

series ordinal

1

1 reference

3 June 2018

language of work or name

English

0 references

publication date

1 December 2008

1 reference

3 June 2018

published in

Nature Medicine

1 reference

3 June 2018

volume

14

1 reference

3 June 2018

issue

12

1 reference

3 June 2018

page(s)

1315-1316

1 reference

3 June 2018

https://scigraph.springernature.com/pub.10.1038/nm1208-1315

exact match

0 references

cites work

Targeting phosphoinositide 3-kinase: moving towards therapy

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

Targeting RAS signalling pathways in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

7 January 2021

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

7 January 2021

High frequency of mutations of the PIK3CA gene in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

7 January 2021

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

7 January 2021

Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

7 January 2021

Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

7 January 2021

AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in precl

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

7 January 2021

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNM1208-1315

7 January 2021

Identifiers

DOI

10.1038/NM1208-1315

1 reference

3 June 2018

1 reference

3 June 2018