(Q33684033)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

main subject

phase II clinical trial

0 references

0 references

1 reference

Antonio Martin-Bastida

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Roberta J Ward

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

David T Dexter

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Paola Piccini

4

1 reference

ORCID Public Data File 2021

author name string

Rexford Newbould

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

David Sharp

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Christina Kabba

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Maneesh C Patel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Michael Spino

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

John Connelly

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Fernando Tricta

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Robert R Crichton

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

language of work or name

English

0 references

publication date

3 May 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

page(s)

1398

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

19 March 2020

copyright license

start time

3 May 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/s41598-017-01402-2

0 references

cites work

Expression of hepcidin at the choroid plexus in normal aging rats is associated with IL-6/Stat3 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Targeting chelatable iron as a therapeutic modality in Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Neuromelanin of the human substantia nigra: an update

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Systemic iron homeostasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Fluid and white matter suppression with the MP2RAGE sequence.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Systematic review of levodopa dose equivalency reporting in Parkinson's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Combined therapy with idebenone and deferiprone in patients with Friedreich's ataxia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Transcranial sonography in brain disorders with trace metal accumulation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Chronic expression of H-ferritin in dopaminergic midbrain neurons results in an age-related expansion of the labile iron pool and subsequent neurodegeneration: implications for Parkinson's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Peripheral cytokines profile in Parkinson's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Redistribution of accumulated cell iron: a modality of chelation with therapeutic implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Peripheral inflammatory biomarkers and risk of Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Interleukin-6 induces hepcidin expression through STAT3

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Inflammatory process in Parkinson's disease: role for cytokines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

The relevance of iron in the pathogenesis of Parkinson's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Alpha-synuclein in Lewy bodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Evaluation of interleukins, ACTH, cortisol and prolactin concentrations in the blood of patients with parkinson's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Increased nigral iron content in postmortem parkinsonian brain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Lipid peroxidation as cause of nigral cell death in Parkinson's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Transferrin and iron uptake by the brain: effects of altered iron status

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

Individual dopaminergic neurons show raised iron levels in Parkinson disease.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-01402-2

Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-01402-2

Selective iron chelation in Friedreich ataxia: biologic and clinical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-01402-2

Increased SNR and reduced distortions by averaging multiple gradient echo signals in 3D FLASH imaging of the human brain at 3T.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-01402-2

Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFalpha, and INFgamma concentrations are elevated in patients with atypical and idiopathic parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-01402-2

Topographical differences of brain iron deposition between progressive supranuclear palsy and parkinsonian variant multiple system atrophy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431100

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity

30 October 2018

1 reference

12 December 2020

The relevance of iron in the pathogenesis of Parkinson's disease

1 reference

12 December 2020

Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson's disease after peripheral administration

1 reference

12 December 2020

Brain iron in the ferrocene-loaded rat: its chelation and influence on dopamine metabolism

1 reference

12 December 2020

10.1038/S41598-017-01402-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

19 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28469157%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference