(Q45227789)

English

Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate

scientific article published in January 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 December 2017

Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

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based on heuristic

inferred from title

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substantia nigra

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based on heuristic

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Moussa B. H. Youdim

3

object named as

Moussa B H Youdim

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Europe PubMed Central

PubMed publication ID

11 December 2017

Silvia A. Mandel

1

object named as

Silvia Mandel

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

2

object named as

Gila Maor

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

language of work or name

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based on heuristic

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publication date

1 January 2004

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Europe PubMed Central

PubMed publication ID

11 December 2017

Journal of Molecular Neuroscience

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Europe PubMed Central

PubMed publication ID

11 December 2017

24

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Europe PubMed Central

PubMed publication ID

11 December 2017

3

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Europe PubMed Central

PubMed publication ID

11 December 2017

401-416

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Europe PubMed Central

PubMed publication ID

11 December 2017

Involvement of iron in MPP+ toxicity in substantia nigra: protection by desferrioxamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection in Parkinson's disease: love story or mission impossible?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rat brain synucleins; family of proteins transiently associated with neuronal membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative mechanisms in nigral cell death in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using cDNA microarray to assess Parkinson's disease models and the effects of neuroprotective drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

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Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fe(II)‐induced DNA damage in α‐synuclein‐transfected human dopaminergic BE(2)‐M17 neuroblastoma cells: detection by the Comet assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hereditary causes of disturbed iron homeostasis in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulation of glutathione contents fails to alter dopaminergic nigrostriatal neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathology of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunolocalization of iron regulatory protein expression in the murine central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synuclein family

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical evaluation of the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on dopaminergic nigrostriatal neurons of young adult mice using dopamine and tyrosine hydroxylase antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological spectrum of synucleinopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian African green monkey: evidence from proton microprobe elemental microanalysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 gene family in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How protein kinase C activation protects nerve cells from oxidative stress-induced cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene and protein expression profiles of anti- and pro-apoptotic actions of dopamine, R-apomorphine, green tea polyphenol (-)-epigallocatechine-3-gallate, and melatonin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine receptor agonist SIB-1508Y improves cognitive functioning in chronic low-dose MPTP-treated monkeys.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rasagiline: an anti-Parkinson drug with neuroprotective activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extrastriatal dopamine D2 and D3 receptors in early and advanced Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in MPTP and 6-hydroxydopamine models: implications for idiopathic Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting programmed cell death in neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early and late gene changes in MPTP mice model of Parkinson's disease employing cDNA microarray

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease: changes in apoptosis-related factors suggesting possible gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed localization of synelfin (synuclein, NACP) to presynaptic terminals in cultured rat hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental expression of alpha-synuclein in rat hippocampus and cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective strategies in Parkinson's disease : an update on progress

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cDNA gene expression profile homology of antioxidants and their antiapoptotic and proapoptotic activities in human neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron, brain ageing and neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apomorphine up-regulates NGF and GDNF synthesis in cultured mouse astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1385/JMN:24:3:401

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

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